Product Info Summary
SKU: | A00811-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | Flow Cytometry, IP, IHC, ICC, WB |
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Product info
Product Name
Anti-COX1 PTGS1 Antibody
SKU/Catalog Number
A00811-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-COX1 PTGS1 Antibody catalog # A00811-1. Tested in WB,ICC,IHC,Flow Cytometry,IP applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-COX1 PTGS1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00811-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human IL-4Ralpha around the phosphorylation site of Y497.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00811-1 is reactive to PTGS1 in Human, Mouse, Rat
Applications
A00811-1 is guaranteed for Flow Cytometry, IP, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
68686 MW
Background of COX-1
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.
Arja Lamberg, J. Biol. Chem., May 1996; 271: 11988.
GW Conrad, J. Cell Biol., Mar 1980; 84: 501.
DR Keene, J. Cell Biol., Nov 1987; 105: 2393.
HM Wang, J. Histochem. Cytochem., Nov 1980; 28: 1215.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000-1:5,000
ICC: 1:100-1:500
IHC: 1:50-1:200
FC: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunocytochemistry staining of PTGS1 using Anti-COX1 PTGS1 Antibody (A00811-1).
ICC staining COX1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeClick image to see more details
Figure 1. Western blotting validation for Anti-COX1 PTGS1 Antibody A00811-1
Western blot analysis of COX1 on different lysates using anti-COX1 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For PTGS1 (Source: Uniprot.org, NCBI)
Gene Name
PTGS1
Full Name
Prostaglandin G/H synthase 1
Weight
68686 MW
Superfamily
prostaglandin G/H synthase family
Alternative Names
COX1; COX-1; COX1PGG/HS; COX3; cyclooxygenase-1; EC 1.14.99.1; PCOX1; PGH synthase 1; PGHS1; PGHS-1PHS1; PHS 1; prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; Prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase andcyclooxygenase); Prostaglandin-endoperoxide synthase 1; PTGHS; PTGS1 PTGS1 COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS prostaglandin-endoperoxide synthase 1 prostaglandin G/H synthase 1|PGH synthase 1|cyclooxygenase-1|prostaglandin H2 synthase 1|prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PTGS1, check out the PTGS1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PTGS1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-COX1 PTGS1 Antibody (A00811-1)
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No publications found for A00811-1
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