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Product Info Summary
| SKU: | A05494 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-CNGA1/Cng1 Antibody
SKU/Catalog Number
A05494
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-CNGA1/Cng1 Antibody (Catalog # A05494). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CNGA1/Cng1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05494)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human CNGA1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05494 is reactive to CNGA1 in Human
Reconstitution
Observed Molecular Weight
111 kDa
Calculated molecular weight
79586 MW
Background of CNG1
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.
Pittler S.J., J. Biol. Chem. 267:6257-6262(1992).
Dhallan R.S., J. Neurosci. 12:3248-3256(1992).
Ota T., Nat. Genet. 36:40-45(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05494 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
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Western blot analysis of extracts from HepG2 cells and K562 cells, using CNGA1 antibody A05494.
Protein Target Info & Infographic
Gene/Protein Information For CNGA1 (Source: Uniprot.org, NCBI)
Gene Name
CNGA1
Full Name
cGMP-gated cation channel alpha-1
Weight
79586 MW
Superfamily
cyclic nucleotide-gated cation channel (TC 1.A.1.5) family
Alternative Names
cGMP-gated cation channel alpha-1;Cyclic nucleotide-gated cation channel 1;Cyclic nucleotide-gated channel alpha-1;CNG channel alpha-1;CNG-1;CNG1;Cyclic nucleotide-gated channel, photoreceptor;Rod photoreceptor cGMP-gated channel subunit alpha;CNGA1;CNCG, CNCG1; CNGA1 CNCG, CNCG1, CNG-1, CNG1, RCNC1, RCNCa, RCNCalpha, RP49 cyclic nucleotide gated channel subunit alpha 1 cGMP-gated cation channel alpha-1|CNG channel alpha-1|cyclic nucleotide gated channel alpha 1|cyclic nucleotide-gated cation channel 1|cyclic nucleotide-gated channel, photoreceptor|interleukin-1 homologue|rod photoreceptor cGMP-gated channel subunit alpha
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CNGA1, check out the CNGA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CNGA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CNGA1/Cng1 Antibody (A05494)
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No publications found for A05494
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