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Product Info Summary
| SKU: | A02966 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-CITED2 Antibody
SKU/Catalog Number
A02966
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CITED2 Antibody (Catalog # A02966). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CITED2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CITED2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02966)
Host
Rabbit
Contents
CITED2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CITED2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CITED2. The immunogen is located within the first 50 amino acids of CITED2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of CITED2 are known to exist.
Reactive Species
A02966 is reactive to CITED2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
28497 MW
Background of Cited-2
CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02966 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CITED2 antibody can be used for detection of CITED2 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CITED2 in Jurkat cell lysate with CITED2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunofluorescence of CITED2 in Jurkat cells with CITED2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CITED2 (Source: Uniprot.org, NCBI)
Gene Name
CITED2
Full Name
Cbp/p300-interacting transactivator 2
Weight
28497 MW
Superfamily
CITED family
Alternative Names
ASD8, MRG1, VSD2, MRG-1, P35SRJ, MSG-related protein 1 CITED2 ASD8, MRG-1, MRG1, P35SRJ, VSD2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 cbp/p300-interacting transactivator 2|MSG-related protein 1|MSG1-related gene 1|melanocyte-specific gene 1-related gene 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CITED2, check out the CITED2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CITED2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CITED2 Antibody (A02966)
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