Anti-CHML/Rep 2 Antibody

Product Name

Anti-CHML/Rep 2 Antibody

View all CHML Antibodies

SKU/Catalog Number

A08815

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-CHML/Rep 2 Antibody (Catalog # A08815). Tested in WB, IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CHML/Rep 2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08815)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human CHML.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A08815 is reactive to CHML in Human

Reconstitution

Calculated molecular weight

74071 MW

Background of CHML

Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.

Cremers F.P.M., Hum. Mol. Genet. 1:71-75(1992).
Kasper G., Gene 295:27-32(2002).
Ota T. Nat. Genet. 36:40-45(2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A08815 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

Gene/Protein Information For CHML (Source: Uniprot.org, NCBI)

Alternative Names

Rab proteins geranylgeranyltransferase component A 2;Choroideremia-like protein;Rab escort protein 2;REP-2;CHML;REP2; CHML REP2 CHM like Rab escort protein rab proteins geranylgeranyltransferase component A 2|CHM like Rab escort protein 2|choroideraemia-like protein|choroideremia-like (Rab escort protein 2)|choroideremia-like protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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