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Product Info Summary
| SKU: | A08747 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Cell adhesion molecule 3 CADM3 Antibody
View all IGSF4B/SynCAM3/CADM3 Antibodies
SKU/Catalog Number
A08747
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Cell adhesion molecule 3 CADM3 Antibody (Catalog # A08747). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CADM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Cell adhesion molecule 3 CADM3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08747)
Host
Rabbit
Contents
CADM3 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CADM3 antibody was raised against a 16 amino acid peptide near the center of human CADM3. The immunogen is located within amino acids 220 - 270 of CADM3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CADM3 antibody is human, mouse and rat reactive. At least three isoforms are known to exist; this antibody will only detect the two longest isoforms. CADM3 antibody is predicted to not cross-react with other members of the CADM protein family.
Reactive Species
A08747 is reactive to CADM3 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
43300 MW
Background of IGSF4B/SynCAM3/CADM3
Cell adhesion molecule 3 (CADM3) is a member of a family of immunoglobulin-like, calcium-independent cell-cell adhesion molecules (1,2). CADM3 localizes to non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes and is thought to play an important role in the formation of synapses, axon bundles and myelinated axons (3). Recently, CADM3 has been shown to suppress the growth and tumorigenic ability of colon cancer cells, indicating that it can act as a tumor suppressor (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08747 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CADM3 antibody can be used for detection of CADM3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CADM3 in human brain tissue lysate with CADM3 antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of CADM3 in mouse brain tissue with CADM3 antibody at 5 μg/ml.
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Immunofluorescence of CADM3 in mouse brain tissue with CADM3 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For CADM3 (Source: Uniprot.org, NCBI)
Gene Name
CADM3
Full Name
Cell adhesion molecule 3
Weight
43300 MW
Superfamily
nectin family
Alternative Names
Cell adhesion molecule 3, BIgR, NECL1, Necl-1, TSLL1, IGSF4B, synCAM3 CADM3 BIgR, IGSF4B, NECL1, Necl-1, TSLL1, synCAM3 cell adhesion molecule 3 cell adhesion molecule 3|TSLC1-like 1|brain immunoglobulin receptor|immunoglobulin superfamily member 4B|synaptic cell adhesion molecule 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CADM3, check out the CADM3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CADM3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cell adhesion molecule 3 CADM3 Antibody (A08747)
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