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CD86 Antibodies
AND CD86 ELISA kits, CD86 Proteins
Many biological assays use antibodies to detect CD86, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD86 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD86 antibodies...
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CD86 Infographic by Boster Bio
All CD86 Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$499
Cat # EK0711
96 wells/kit, with removable strips.
Cat # EK0711
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # EK0712
96 wells/kit, with removable strips.
Cat # EK0712
96 wells/kit, with removable strips.
Human, Mouse, Rat
Flow Cytometry, IF, IHC, Functional Assay
$486
Cat # M00220
100ug/vial
Cat # M00220
100ug/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00220-1
100 μl
Cat # M00220-1
100 μl
Cynomolgus monkey, Human, Baboon, Rhesus monkey
Flow Cytometry
$223
Cat # FC00220
100ug, 500ug
Cat # FC00220
100ug, 500ug
Cynomolgus monkey, Human, Baboon, Rhesus monkey
Flow Cytometry
$299
Cat # FC00220-PE
100 tests, 200 tests
Cat # FC00220-PE
100 tests, 200 tests
Cynomolgus monkey, Human, Baboon, Rhesus monkey
Flow Cytometry
$325
Cat # FC00220-APC
100 tests, 200 tests
Cat # FC00220-APC
100 tests, 200 tests
Mouse
Flow Cytometry, IP, IHC-F, ICC
$299
Cat # M00220-2
0.1 mg
Cat # M00220-2
0.1 mg
Anti-Cd86 Antibody Picoband®
2 Citations
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00220-4
100 μg/vial
Cat # A00220-4
100 μg/vial
CD86 Overview
Facts about T-lymphocyte activation antigen CD86.
T-lymphocyte activation antigen CD86 (CD86)
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 manufacturing, by binding CD28 or CTLA-4. May play a vital role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between resistance and anergy that is made by T- cells within 24 hours after activation.
Isoform 2 interferes with the formation of CD86 clusters, and thus functions as a negative regulator of T-cell activation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CD86 |
| Uniprot: | P42081 |
| Entrez: | 942 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Activation B7-2 antigen; B70; B7-2 antigen; B72; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; CD28LG2B7-2 antigen); CD86 antigen; CD86 molecule; CD86; CTLA-4 counter-receptor B7.2; FUN-1; LAB72; MGC34413; T-lymphocyte activation antigen CD86
Molecular Weight
Mass (kDA):
37.682 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q13.33 |
| Sequence: | 3; NC_000003.12 (122055362..122121143) |
Tissue Specificity
Expressed by activated B-lymphocytes and monocytes.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Autoimmune Reaction
- Tissue Adhesions
- Autoimmune Diseases
- Leukemia
- Decreased Immunologic Activity [pe]
- Autoimmunity
- Carcinoma
- Infective Disorder
- Asthma
- Hiv Infections
Interacting Proteins
- CTLA4
Pathways
- Immune Response
- Secretion
- Cell Activation
- Cell Proliferation
- Cytokine Production
- T Cell Activation
- T Cell Proliferation
- Pathogenesis
- Sensitization
- Cell Maturation
- Cell Differentiation
- Phagocytosis
- Hypersensitivity
PTMs
- Phosphorylation
- Methylation
- Ubiquitination
- Cleavage
- Glycosylation
- Acetylation
- Reduction
- Ribosylation
- Phosphorothioation
- Biotinylation
Research Areas
- Adaptive Immunity
- Cell Cycle and Replication
- Dendritic Cell Markers
- Diabetes Research
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD86
bosterbio.com/bosterbio-gene-info-cards/CD86
References
PMID: 7694153 by Azuma M., et al. B70 antigen is a second ligand for CTLA-4 and CD28.
PMID: 7694363 by Freeman G.J., et al. Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation.
3 Publications of Boster CD86 Antibodies & ELISA Kits
- PubMed ID: 10.1080/17435390.2018.1425501, Macrophage polarization and activation at the interface of multi-walled carbon n...
- PubMed ID: 10.1016/j.brainresbull.2019.07.019, Lithium chloride promoted hematoma resolution after intracerebral hemorrhage thr...
- PubMed ID: , Near infrared light-triggered on-demand Cur release from Gel-PDA@Cur composite h...
*More publications can be found for each product on its corresponding product page