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Product Info Summary
| SKU: | A15044-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-CCDC106 Antibody
SKU/Catalog Number
A15044-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CCDC106 Antibody (Catalog # A15044-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CCDC106 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CCDC106 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15044-1)
Host
Rabbit
Contents
CCDC106 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CCDC106 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CCDC106. The immunogen is located within the last 50 amino acids of CCDC106.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Two isoforms of IRGC are known to exist; this antibody will recognize both isoforms.
Reactive Species
A15044-1 is reactive to CCDC106 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
32032 MW
Background of CCDC106
The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A15044-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CCDC106 antibody can be used for detection of CCDC106 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CCDC106 in human brain tissue lysate with CCDC106 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of CCDC106 in rat brain tissue with CCDC106 antibody at 5 μg/mL.
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Immunofluorescence of CCDC106 in rat brain tissue with CCDC106 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CCDC106 (Source: Uniprot.org, NCBI)
Gene Name
CCDC106
Full Name
Coiled-coil domain-containing protein 106
Weight
32032 MW
Alternative Names
ZNF581, HSU79303, Coiled-coil domain-containing protein 106 CCDC106 HSU79303, ZNF581 coiled-coil domain containing 106 coiled-coil domain-containing protein 106|protein predicted by clone 23882
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CCDC106, check out the CCDC106 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CCDC106: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CCDC106 Antibody (A15044-1)
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