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Product Info Summary
| SKU: | PA1540 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Caveolin-2/CAV2 Antibody Picoband®
View all Caveolin-2 Antibodies
SKU/Catalog Number
PA1540
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Caveolin-2/CAV2 Antibody catalog # PA1540. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Caveolin-2/CAV2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1540)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Caveolin-2, different from the related rat and mouse sequences by one amino acid.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1540 is reactive to CAV2 in Human, Mouse, Rat
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
17 kDa
Calculated molecular weight
18291 MW
Background of Caveolin-2
Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Caveolin-1 and caveolin-2 are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of CAV1 and CAV2 are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA1540 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Positive Control
WB: Rat Heart Tissue, Rat lung Tissue, HELA Cell, A431 Cell, HELA Whole Cell, SMMC Whole Cell, COLO320 Whole Cell
IHC: Human Lung Cancer Tissue, Rat Cardiac Muscle Tissue
Validation Images & Assay Conditions
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Anti-Caveolin-2 antibody, PA1540, Western blotting
Lane 1: Rat Heart Tissue Lysate
Lane 2: Rat lung Tissue Lysate
Lane 3: HELA Cell Lysate
Lane 4: A431 Cell Lysate
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Anti-Caveolin-2 antibody, PA1540, Western blotting
All lanes: Anti Caveolin-2 (PA1540) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: SMMC Whole Cell Lysate at 40ug
Lane 3: COLO320 Whole Cell Lysate at 40ug
Predicted bind size: 17KD
Observed bind size: 17KD
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Anti-Caveolin-2 antibody, PA1540, IHC(P)
IHC(P): Human Lung Cancer Tissue
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Anti-Caveolin-2 antibody, PA1540, IHC(P)
IHC(P): Rat Cardiac Muscle Tissue
Protein Target Info & Infographic
Gene/Protein Information For CAV2 (Source: Uniprot.org, NCBI)
Gene Name
CAV2
Full Name
Caveolin-2
Weight
18291 MW
Superfamily
caveolin family
Alternative Names
Caveolin-2;CAV2; CAV2 CAV caveolin 2 caveolin-2|caveolae protein, 20-kD
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CAV2, check out the CAV2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CAV2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Caveolin-2/CAV2 Antibody Picoband® (PA1540)
Hello CJ!
PA1540 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Wang Nn, Zhao Lj, Wu Ln, He Mf, Qu Jw, Zhao Yb, Zhao Wz, Li Js, Wang Jh. Asian Pac J Cancer Prev. 2013;14(9):4983-8. Mechanistic Analysis Of Taxol-Induced Multidrug Resistance In An Ovarian Cancer Cell Line.
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