Anti-Caspase-6(P18)/CASP6 Antibody Picoband®

Product Name

Anti-Caspase-6(P18)/CASP6 Antibody Picoband®

View all Caspase-6 Antibodies

SKU/Catalog Number

PA1441-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Caspase-6 (P18)/CASP6 Antibody catalog # PA1441-1. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Caspase-6(P18)/CASP6 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1441-1)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of rat Caspase-6(P18), different from the related mouse sequence by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1441-1 is reactive to Casp6 in Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

35 kDa

Calculated molecular weight

31556 MW

Background of Caspase-6

Caspase 6 is an enzyme that in humans is encoded by the caspase 6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Using radiation hybrid mapping, the Caspase 6 gene is localized to human chromosome 4q25-q26. Caspase 6 functions as a downstream enzyme in the caspase activation cascade. And Caspase 6 can cleave lamin A to its signature apoptotic fragment.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1441-1 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, By Heat
Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Rat, Mouse
Western blot, 0.1-0.5μg/ml, Mouse, Rat

Positive Control

WB: Rat Liver Tissue, Rat Kidney Tissue, Rat Testis Tissue, NRK Cell, Mouse Liver Tissue, Mouse Kidney Tissue, Mouse Testis Tissue
IHC: Rat Spleen Tissue, Rat Intestine Tissue, Mouse Lung Tissue
IHC-F: Rat Spleen Tissue

Validation Images & Assay Conditions

Gene/Protein Information For Casp6 (Source: Uniprot.org, NCBI)

Alternative Names

Caspase-6;CASP-6;3.4.22.59;Apoptotic protease Mch-2;Caspase-6 subunit p18;Caspase-6 subunit p11;Casp6;Mch2; CASP6 MCH2 caspase 6 caspase-6|apoptotic protease MCH-2|caspase 6, apoptosis-related cysteine peptidase|caspase 6, apoptosis-related cysteine protease

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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