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Caspase-6 Antibodies
AND CASP6 ELISA kits, Caspase-6 Proteins
Many biological assays use antibodies to detect Caspase-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-6 antibodies...
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CASP6 Infographic by Boster Bio
All CASP6 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IHC, WB
$370
Cat # PA1441
100 μg/vial
Cat # PA1441
100 μg/vial
Mouse, Rat
IHC, WB
$370
Cat # PA1441-1
100 μg/vial
Cat # PA1441-1
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M02631-2
100 μl
Cat # M02631-2
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02631
100 μl
Cat # M02631
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1087
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1087
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1975
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1975
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A02631S257-1
100ul
Cat # A02631S257-1
100ul
Human, Mouse, Rat
IHC, WB
$370
Cat # M02631-4
100 µl/vial
Cat # M02631-4
100 µl/vial
CASP6 Overview
Facts about Caspase-6.
Caspase-6 (CASP6)
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, in addition to lamins.
Overexpression promotes programmed cell death. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CASP6 |
| Uniprot: | P55212 |
| Entrez: | 839 |
Family
| Belongs to: |
|---|
| peptidase C14A family |
Alternative Names
Apoptotic protease Mch-2; CASP6; CASP-6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; Caspase6; Caspase-6; EC 3.4.22; Mch2; MCH2EC 3.4.22.59
Molecular Weight
Mass (kDA):
33.31 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q25 |
| Sequence: | 4; NC_000004.12 (109688628..109703445, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Alzheimer's Disease
- Carcinoma
- Leukemia
- Huntington Disease
- Malignant Neoplasm Of Breast
- Malignant Paraganglionic Neoplasm
- Nerve Degeneration
- Neurodegenerative Disorders
- Mammary Neoplasms
- Tissue Adhesions
- Glioma
Interacting Proteins
- CASP3
- SATB1
Pathways
- Cell Death
- Proteolysis
- Pathogenesis
- Localization
- Induction Of Apoptosis
- Programmed Cell Death
- Cell Cycle
- Apoptotic Process
- Cell Proliferation
- Cell Differentiation
- Translation
- Neuroprotection
- Cellular Homeostasis
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Deacetylation
- Acetylation
Research Areas
- Apoptosis
- Cancer
- Caspases
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CASP6
bosterbio.com/bosterbio-gene-info-cards/CASP6
References
PMID: 7796396 by Fernandes-Alnemri T., et al. Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family.
PMID: 8900201 by Srinivasula S.M., et al. The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.