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Product Info Summary
| SKU: | A15152-2 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Calcium-binding protein 7 CaBP7 Antibody
SKU/Catalog Number
A15152-2
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Calcium-binding protein 7 CaBP7 Antibody (Catalog # A15152-2). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CaBP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Calcium-binding protein 7 CaBP7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15152-2)
Host
Rabbit
Contents
CaBP7 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CaBP7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CaBP7. The immunogen is located within the first 50 amino acids of CaBP7.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of SPATA4 are known to exist; this antibody will detect both isoforms. SPATA4 antibody is predicted to not cross-react with SPATA protein family members
Reactive Species
A15152-2 is reactive to CABP7 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
24453 MW
Background of CABP7
Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A15152-2 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CaBP7 antibody can be used for detection of CaBP7 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 4 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CaBP7 in Hela cell lysate with CaBP7 antibody at (A) 1 and (B) 2 μg/mL.
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Immunocytochemistry of CaBP7 in HeLa cells with CaBP7 antibody at 4 μg/mL.
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Immunofluorescence of CABP7 in HeLa cells with CAPB7 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CABP7 (Source: Uniprot.org, NCBI)
Gene Name
CABP7
Full Name
Calcium-binding protein 7
Weight
24453 MW
Alternative Names
CALN2, CALN2, Calcium-binding protein 7, Calneuron II, CaBP7 CABP7 CALN2 calcium binding protein 7 calcium-binding protein 7|calneuron 2|calneuron II
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CABP7, check out the CABP7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CABP7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Calcium-binding protein 7 CaBP7 Antibody (A15152-2)
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