Product Info Summary
SKU: | A08841 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-C2 domain-containing protein 3 C2CD3 Antibody
SKU/Catalog Number
A08841
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-C2 domain-containing protein 3 C2CD3 Antibody (Catalog # A08841). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
C2CD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-C2 domain-containing protein 3 C2CD3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08841)
Host
Rabbit
Contents
C2CD3 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
C2CD3 antibody was raised against an 18 amino acid peptide near the center of human C2CD3. The immunogen is located within amino acids 1490 - 1540 of C2CD3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
C2CD3 antibody is human, mouse and rat reactive.
Reactive Species
A08841 is reactive to C2CD3 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
260389 MW
Background of C2CD3
C2CD3, a putative calcium-dependent lipid-binding protein, is an essential regulator of intracellular transduction of the Hedgehog signal (1). It is localized at the basal body of cilia, mediates calcium-dependent vesicular transport and/or recruitment of proteins and regulates cilium biogenesis by promoting the assembly of centriolar distal appendages critical for docking ciliary vesicles and recruiting other essential ciliogenic proteins (2,3). C2CD3 directly promotes centriole elongation and OFD1 acts as a negative regulator of C2CD3 (4,5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08841 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
C2CD3 antibody can be used for detection of C2CD3 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
![a08841 anti c2 domain containing protein 3 c2cd3 antibody wb testing 1 a08841 anti c2 domain containing protein 3 c2cd3 antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a08841-anti-c2-domain-containing-protein-3-c2cd3-antibody-wb-testing-1.jpg)
Click image to see more details
Western blot analysis of C2CD3 in EL4 cell lysate with C2CD3 antibody at (A) 1 and (B) 2 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For C2CD3 (Source: Uniprot.org, NCBI)
Gene Name
C2CD3
Full Name
C2 domain-containing protein 3
Weight
260389 MW
Alternative Names
C2 calcium-dependent domain containing 3, C2 domain-containing protein 3 C2CD3 OFD14 C2 domain containing 3 centriole elongation regulator C2 domain-containing protein 3|C2 calcium dependent domain containing 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on C2CD3, check out the C2CD3 Infographic
![C2CD3 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for C2CD3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-C2 domain-containing protein 3 C2CD3 Antibody (A08841)
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