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Product Info Summary
| SKU: | PA1504 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-B-cell lymphoma/leukemia 10 Bcl10 Antibody Picoband®
SKU/Catalog Number
PA1504
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-B-cell lymphoma/leukemia 10 Bcl10 Antibody catalog # PA1504. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-B-cell lymphoma/leukemia 10 Bcl10 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1504)
Host
Rabbit
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2mg Na2HPO4.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Bcl10, identical to the related rat and mouse sequences.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1504 is reactive to BCL10 in Human, Mouse, Rat
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
37 kDa
Calculated molecular weight
26252 MW
Background of Bcl-10
BCL10, B-cell CLL/lymphoma 10, gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The BCL10 gene is mapped to chromosome 1p22. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are though to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are though to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA1504 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Positive Control
WB: U87 Cell, MCF-7 Cell, HELA Cell, COLO320 Cell
Validation Images & Assay Conditions
Click image to see more details
Anti-Bcl10 antibody, PA1504, Western blotting
Lane 1: U87 Cell Lysate
Lane 2: MCF-7 Cell Lysate
Lane 3: HELA Cell Lysate
Lane 4: COLO320 Cell Lysate
Protein Target Info & Infographic
Gene/Protein Information For BCL10 (Source: Uniprot.org, NCBI)
Gene Name
BCL10
Full Name
B-cell lymphoma/leukemia 10
Weight
26252 MW
Alternative Names
B-cell lymphoma/leukemia 10;B-cell CLL/lymphoma 10;Bcl-10;CARD-containing molecule enhancing NF-kappa-B;CARD-like apoptotic protein;hCLAP;CED-3/ICH-1 prodomain homologous E10-like regulator;CIPER;Cellular homolog of vCARMEN;cCARMEN;Cellular-E10;c-E10;Mammalian CARD-containing adapter molecule E10;mE10;BCL10;CIPER, CLAP; BCL10 CARMEN, CIPER, CLAP, IMD37, c-E10, mE10 BCL10 immune signaling adaptor B-cell lymphoma/leukemia 10|B cell CLL/lymphoma 10|CARD containing molecule enhancing NF-kB|CARD-containing apoptotic signaling protein|CARD-containing molecule enhancing NF-kappa-B|CARD-containing proapoptotic protein|CED-3/ICH-1 prodomain homologous E10-like regulator|cCARMEN|caspase-recruiting domain-containing protein|cellular homolog of vCARMEN|cellular-E10|hCLAP|mammalian CARD-containing adapter molecule E10
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BCL10, check out the BCL10 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BCL10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-B-cell lymphoma/leukemia 10 Bcl10 Antibody Picoband® (PA1504)
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