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Product Info Summary
| SKU: | M00322 |
|---|---|
| Size: | 100 μl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IP, WB |
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Product info
Product Name
Anti-BACE1/Bace Rabbit Monoclonal Antibody
SKU/Catalog Number
M00322
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-BACE1/Bace Rabbit Monoclonal Antibody catalog # M00322. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-BACE1/Bace Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00322)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
ABFF-2
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human BACE1
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00322 is reactive to BACE1 in Human, Mouse, Rat
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Observed Molecular Weight
47 kDa
Calculated molecular weight
55711 MW
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00322 is guaranteed for IP, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IP 1:40
Validation Images & Assay Conditions
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
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Western blot analysis of BACE1 expression in SH-SY5Y cell lysate.
Protein Target Info & Infographic
Gene/Protein Information For BACE1 (Source: Uniprot.org, NCBI)
Gene Name
BACE1
Full Name
Beta-secretase 1
Weight
55711 MW
Superfamily
peptidase A1 family
Alternative Names
Beta-secretase 1;3.4.23.46;Aspartyl protease 2;ASP2;Asp 2;Beta-site amyloid precursor protein cleaving enzyme 1;Beta-site APP cleaving enzyme 1;Memapsin-2;Membrane-associated aspartic protease 2;BACE1;BACE, KIAA1149; BACE1 ASP2, BACE, HSPC104 beta-secretase 1 beta-secretase 1|APP beta-secretase|asp 2|aspartyl protease 2|beta-secretase 1 precursor variant 1|beta-site APP cleaving enzyme 1|beta-site APP-cleaving enzyme|beta-site amyloid beta A4 precursor protein-cleaving enzyme|memapsin-2|membrane-associated aspartic protease 2|transmembrane aspartic proteinase Asp2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BACE1, check out the BACE1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BACE1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-BACE1/Bace Rabbit Monoclonal Antibody (M00322)
Hello CJ!
M00322 has been cited in 2 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Wu J,Qu JQ,Zhou YJ,Zhou YJ,Li YY,Huang NQ,Deng CM,Luo Y.Icariin improves cognitive deficits by reducing the deposition of β-amyloid peptide and inhibition of neurons apoptosis in SAMP8 mice.Neuroreport.2020 Jun 7;31(9):663-671.doi:10.1097/WNR.000000000000
Species: Mouse
M00322 usage in article: APP:WB, SAMPLE:HIPPOCAMPUS TISSUE, DILUTION:NA
Expression of ?-site APP-cleaving enzyme 1 in the hippocampal tissue of an insulin-resistant rat model of Alzheimer's disease
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-BACE1/Bace Rabbit Monoclonal Antibody
Question
We are currently using anti-BACE1/Bace Rabbit Monoclonal antibody M00322 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on monkey tissues as well?
A. Yang
Verified customer
Asked: 2013-03-26
Answer
The anti-BACE1/Bace Rabbit Monoclonal antibody (M00322) has not been tested for cross reactivity specifically with monkey tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2013-03-26
