AK4 Antibodies

AND AK4 ELISA kits, AK4 Proteins

Many biological assays use antibodies to detect AK4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AK4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AK4 antibodies...

We validate the specificity of these antibodies to AK4 by testing them on tissues known to express AK4 positively and negatively. Browse below to find the AK4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AK4 Infographic by Boster Bio

All AK4 Products

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Product

Figures

Specificity

Applications

Price

AK3L1 (AK4) (NM_013410) Human Recombinant Protein

$813
Cat # PROTP27144
20 µg

Anti-AK3L1 (AK4) Mouse Monoclonal Antibody [Clone ID: OTI3B1]

+12

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M07383
100 µl

Anti-Adenylate kinase 4 Rabbit Monoclonal Antibody

Human

IF, IHC, ICC, WB

$370
Cat # M07383-1
100 μl/vial

AK4 Overview

Facts about Adenylate kinase 4, mitochondrial.

AK4 3D structure. Source: alphafold

Adenylate kinase 4, mitochondrial (AK4)

Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP with ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor.

Also displays broad nucleoside diphosphate kinase activity. .

Gene Information

Human
Gene Name:	AK4
Uniprot:	P27144
Entrez:	205

Family

Belongs to:

adenylate kinase family

Alternative Names

adenylate kinase 3; adenylate kinase 3-like 1; Adenylate kinase 3-like; adenylate kinase 4; AK3adenylate kinase isoenzyme 4, mitochondrial; AK3L1; AK3L2; ATP-AMP transphosphorylase; EC 2.7.4; EC 2.7.4.3; GTP:AMP phosphotransferase; MGC166959; mitochondrial adenylate kinase-3; nucleoside-triphosphate-adenylate kinase

Molecular Weight

Mass (kDA):
25.268 kDA

Genomic Context


Human

Location:	1p31.3
Sequence:	1; NC_000001.11 (65147342..65232145)

Tissue Specificity

Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain.

Subcellular Localizations

Mitochondrion matrix.

Diseases

Leukemia, Experimental
Leukemia
Hypoxia
Tissue Adhesions
Sclerosis
Cystic Fibrosis
Neoplasm Metastasis
Primary Lateral Sclerosis
Stenosis
Neurodegenerative Disorders
Neoplasms, Experimental
Liver Damage

Amyotrophic Lateral Sclerosis
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Age Related Macular Degeneration
Vascular System Injuries
Malignant Neoplasms
Nervousness

Pathways

Localization
Cell Adhesion
Cell Activation
Cell Proliferation
Cell Death
Respiratory Burst

Hemostasis

PTMs

Phosphorylation

Biotinylation

Nitration

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AK4

References

PMID: 1639383 by Xu G., et al. Characterization of human adenylate kinase 3 (AK3) cDNA and mapping of the AK3 pseudogene to an intron of the NF1 gene.

PMID: 11485571 by Noma T., et al. Structure and expression of human mitochondrial adenylate kinase targeted to the mitochondrial matrix.