TNFSF18 Antibodies

AND TNFSF18 ELISA kits, TNFSF18 Proteins

Many biological assays use antibodies to detect TNFSF18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFSF18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFSF18 antibodies...

We validate the specificity of these antibodies to TNFSF18 by testing them on tissues known to express TNFSF18 positively and negatively. Browse below to find the TNFSF18 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNFSF18 Infographic by Boster Bio

All TNFSF18 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Mouse TNFSF18/GITRL ELISA Kit PicoKine®

10 Q&As

Mouse

ELISA

$499
Cat # EK1308
96 wells/kit, with removable strips.

Anti-TNFSF18 Antibody Picoband®

1 Q&As

Human

ELISA, IHC, WB

$370
Cat # A04408-1
100 μg/vial

Anti-GITRL TNFSF18 Antibody

Human, Mouse

ELISA, ICC, WB

$449
Cat # A04408
0.1 mg

Anti-TNFSF18 Antibody

Human, Mouse, Rat

$405
Cat # A04408-2
100ul

Human GITR Ligand/TNFSF18 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9UNG2
Starting from 20ug

TNFSF18 (NM_005092) Human Over-expression Lysate

Human

$628
Cat # LS008995
100 µg

Human recombinant AITRL (Activation-induced TNFR member ligand) protein, AF

Human

Cell Culture

$77
Cat # PROTQ9UNG2-7
5ug,20ug,100ug,500ug,1mg

TNFSF18 Overview

Facts about Tumor necrosis factor ligand superfamily member 18.

TNFSF18 3D structure. Source: alphafold

Tumor necrosis factor ligand superfamily member 18 (TNFSF18)

Regulates T- cell responses. Can be costimulator and lower the threshold for T-cell activation and T-cell proliferation.

Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.

Gene Information

Human
Gene Name:	TNFSF18
Uniprot:	Q9UNG2
Entrez:	8995

Family

Belongs to:

tumor necrosis factor family

Alternative Names

Activation-inducible TNF-related ligand; AITRL; AITRLMGC138237; GITR Ligand; GITRL; GITRLglucocorticoid-induced TNFR-related protein ligand; Glucocorticoid-induced TNF-related ligand; hGITRLGITR ligand; TL6AITR ligand; TNFSF18; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand superfamily member 18

Molecular Weight

Mass (kDA):
22.724 kDA

Genomic Context


Human

Location:	1q25.1
Sequence:	1; NC_000001.11 (173041220..173050963, complement)

Tissue Specificity

Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.

Subcellular Localizations

Cell membrane; Single-pass type II membrane protein.

Diseases

Inflammation
Neoplasms
Malignant Neoplasms
Autoimmune Reaction
Tissue Adhesions
Autoimmune Diseases
Decreased Immunologic Activity [pe]
Autoimmunity
Rheumatoid Arthritis
Arthritis
Melanoma
Infective Disorder

Malignant Neoplasm Of Breast
Dermatitis, Atopic
Communicable Diseases
Dermatitis
Hiv Infections
Leukemia
Immunologic Deficiency Syndromes

Interacting Proteins

TNFRSF18

Pathways

Immune Response
Pathogenesis
Cytokine Production
Cell Proliferation
Cell Death
Secretion
Cell Activation
Chemokine Production
T Cell Activation
Inflammatory Response
T Cell Proliferation
Angiogenesis
Transport

Cell Adhesion
Osteoclast Differentiation
Transposition
Acute Inflammatory Response
Cell Migration
Platelet Activation
Pigmentation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFSF18

References

PMID: 10074428 by Gurney A.L., et al. Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.

PMID: 10037686 by Kwon B., et al. Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand.