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PDGFB Antibodies
AND PDGFB ELISA kits, PDGFB Proteins
Many biological assays use antibodies to detect PDGFB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDGFB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDGFB antibodies...
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PDGFB Infographic by Boster Bio
All PDGFB Products
Product
Figures
Specificity
Applications
Price
Anti-PDGF beta/PDGFB Antibody Picoband®
2 Citations 4 Q&As
Human, Mouse, Rat
WB
$370
Cat # PB9311
100 μg/vial
Cat # PB9311
100 μg/vial
Anti-PDGF beta/PDGFB Antibody Picoband®
3 Citations
Human, Mouse, Rat
WB
$370
Cat # A00348
100 μg/vial
Cat # A00348
100 μg/vial
Human
$250
Cat # PROTP01127
2ug, 10ug, 1mg
Cat # PROTP01127
2ug, 10ug, 1mg
Mouse
$250
Cat # PROTP31240
2ug, 10ug, 1mg
Cat # PROTP31240
2ug, 10ug, 1mg
Rat
$250
Cat # PROTQ05028
2ug, 10ug, 1mg
Cat # PROTQ05028
2ug, 10ug, 1mg
PDGFB Overview
Facts about Platelet-derived growth factor subunit B.
Platelet-derived growth factor subunit B (PDGFB)
Growth factor that plays a vital role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395).
Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel growth, and for normal development of kidney glomeruli.
Gene Information
| Human | |
|---|---|
| Gene Name: | PDGFB |
| Uniprot: | P01127 |
| Entrez: | 5155 |
Family
| Belongs to: |
|---|
| PDGF/VEGF growth factor family |
Alternative Names
PDGFBB; PDGF-BB
Molecular Weight
Mass (kDA):
27.283 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q13.1 |
| Sequence: | 22; NC_000022.11 (39223359..39244982, complement) |
Tissue Specificity
Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung.
Subcellular Localizations
Secreted. Released by platelets upon wounding.
Diseases
- Neoplasms
- Dermatofibrosarcoma
- Dermatofibrosarcoma Protuberans
- Skin Neoplasms
- Malignant Neoplasms
- Neoplasm Metastasis
- Tumor Angiogenesis
- Malignant Paraganglionic Neoplasm
- Pathologic Neovascularization
- Chromosomal Translocation
- Cell Transformation, Neoplastic
- Glioma
Interacting Proteins
- PDGFRA
- PDGFRB
Pathways
- Angiogenesis
- Localization
- Cell Proliferation
- Pathogenesis
- Cell Growth
- Reverse Transcription
- Cell Adhesion
- Cell Migration
- Cell Cycle
- Regeneration
- Endothelial Cell Proliferation
- Inflammatory Response
- Wound Healing
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDGFB
bosterbio.com/bosterbio-gene-info-cards/PDGFB
References
PMID: 6740330 by Josephs S.F., et al. Transforming potential of human c-sis nucleotide sequences encoding platelet-derived growth factor.
PMID: 4033772 by Collins T., et al. Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis.
4 Publications of Boster PDGFB Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.bios.2011.06.018, Electrochemical immunosensor based on electron transfer mediated by graphene oxi...
- PubMed ID: 22977587, Investigation of the protective effect of erythropoietin on spinal cord injury i...
- PubMed ID: 22977585, Hong Z, Hong H, Chen H, Wang Z, Hong D. Exp Ther Med. 2011 Sep;2(5):837-841. Epu...
- PubMed ID: 22842774, Zhao Yj, Wang H, Liu X, Sun M, Kazuhiro H. Mol Med Rep. 2012 Oct;6(4):739-44. Do...
*More publications can be found for each product on its corresponding product page