Newsletter Archive

Merry Christmas and Happy Holidays from all of us at Boster!

Boster offers a full range of high quality buffers, reagents, and kits for everyday lab use. Save over 50% compared to leading brands & stock up on essential items for your lab.

In the lab, researchers invest time and effort to optimize the sample preparation and sample staining processes of IHC. When successful, the results produce a strong and specific signal.

Picoband™ antibodies are designed and screened using Boster's proprietary optimization system, which enables the antibodies to react to the target protein with high affinity and ensure minimum cross-reactivity with its family members and other sources of non-specific binding.

Allergies are when the body’s immune system has a hypersensitive reaction towards innocuous substances called allergens. Common allergens include dust mites, pollen, mold, food, and animal dander, which could trigger allergic disorders such as allergic asthma, hay fever, allergic rhinitis, anaphylaxis, allergic conjunctivitis, and contact dermatitis.

Boster has partnered with Quansys Biosciences to provide Q-Plex™ Multiplex ELISA kits that allow for concurrent measurement of multiple biomarkers. Each kit contains a 96-well plate of the relevant biomarker panel and includes all required reagents to perform testing. Using just 25 µl of sample per well, up to 80 samples can be assayed for all markers in the panel within 2.5 hours.

ELISA is one of the most commonly performed bioassays that produces qualitative, semi-quantitative, and quantitative data. In order to obtain quantitative ELISA data, constructing the ELISA standard curve is an important and crucial process to estimate the target protein concentrations for your samples.

Flow cytometry is a popular cell biology technique that utilizes laser-based technology to count, sort, and profile cells in a heterogeneous fluid mixture. It is a powerful tool that allows simultaneous multiparametric analysis of the physical and chemical characteristics of up to thousands of particles per second.

Cytokines are a large category of signaling molecules (~5–20 kDa) acting as immunomodulating agents for autocrine signaling, paracrine signaling, and endocrine signaling.

Neuroscience 2019 is taking place October 19-23 at McCormick Place in Chicago. Join 30,000 scientists from around the world to discover hot topics and tools for neuroscience.

Choosing the right antibody can get complicated, so it’s not surprising that customers frequently ask us questions like, “If this antibody is validated for human, will it cross-react with rat, too?” In this technical blog, we review the concept of cross-reactivity, go through the basic steps for determining antibody cross-reactivity, and provide an example.

October is Breast Cancer Awareness Month, a global annual campaign that unites organizations around the world to raise awareness for breast cancer, and highlights the importance of breast cancer education and research.

Our team of experts is dedicated to provide services that are tailored to your needs and specifications. We are committed to being transparent about the timeline, the costs involved, and the progress of your project. A project manager will be assigned to your project to answer all your questions.

In normal conditions, mutated antigens from tumor cells will lead to the activation of T cells that bind to and trigger apoptosis in target cancer cells. On the surface of T cells are PD-1 (programmed cell death-1) receptors whose ligands include PD-L1 and PD-L2.

Boster will be attending 2 exciting events and we hope to see you there!

September is World Alzheimer’s Month, an international campaign to raise dementia awareness and challenge stigma, and the purple ribbon is the chosen color to represent awareness for Alzheimer’s disease.

To set up a standard curve, ELISA standards should be carefully prepared for accurate sample quantification of the target protein. We’ve provided some guidelines for you to consider when preparing ELISA standards.

Boster now offers 1300+ rabbit monoclonal antibodies validated for many applications including flow cytometry, IP, IF, IHC, ICC, WB, and ELISA. The rabbit immune system has historically been useful for generating a larger diversity of high affinity antibodies, including phospho-peptides, carbohydrates, and immunogens not immunogenic in mouse. Search our catalog for your gene target today, and get better results with Boster!

CTLA4 (cytotoxic T-lymphocyte–associated antigen 4, aka CD152) is a transmembrane protein member of the immunoglobin superfamily. This protein receptor plays a key role in downregulating immune responses (e.g., inhibit T-cell activation).

To best serve the research communities where suitable antibodies are hard to find, Boster provides a special discounted custom antibody production service for researchers who use non-mammalian models such as Zebrafish, Drosophila, C. elegans, and Yeast.

Sample fixation is a crucial step for every successful IHC/ICC experiment. During the tissue preparation process, appropriate sample fixation can help preserve morphology, prevent tissue degradation, ensure antigenicity, and protect cells from damage.

This upcoming Sunday, July 28th, is World Hepatitis Day, an annual international awareness event for 325 million people globally affected by hepatitis. World Hepatitis Day is one of WHO's four disease-specific global health days that is supported by organizations such as the World Hepatitis Alliance, HHS, and CDC.

Toll-like receptors (TLRs) are immune receptors localized to the cell surface or intracellular compartments like the endosome. TLRs’ ability to recognize pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) make them key players in innate immunity.

We've partnered with Quansys Biosciences to provide Q-Plex™ Multiplex ELISA kits that allow for concurrent measurement of multiple biomarkers. Each kit contains a 96-well plate of the relevant biomarker panel and includes all required reagents to perform testing. Using just 50 µl of sample per well, up to 80 samples can be assayed for all markers in the panel within 2.5 hours.

Boster has partnered with Quansys Biosciences to provide Q-Plex™ Multiplex ELISA kits that allow for concurrent measurement of multiple biomarkers. Each kit contains a 96-well plate of the relevant biomarker panel and includes all required reagents to perform testing. Using just 50 µl of sample per well, up to 80 samples can be assayed for all markers in the panel within 2.5 hours.

As the most abundant free amino acid in the plasma, glutamine participates in a variety of biochemical processes, such as protein and lipid synthesis, cellular energy production, and nitrogen and carbon donation.

ELISA is a convenient and simple method to quantitatively or qualitatively detect peptides, proteins, antibodies, and hormones in samples, rendering it as one of the most widely used immunoassays.

CD40, a costimulatory protein member of the TNFR superfamily, has been identified to regulate a broad range of cellular responses, including proliferation, differentiation, and cell death. CD40 can be found on several cell types, such as B cells, macrophages, dendritic cells, and fibroblasts, demonstrating its critical role in immune response and host defense. The binding of CD40L to CD40 stimulates APCs and leads to a number of downstream effects. Different gene expression patterns are activated by CD40 for certain cell types. In addition, several pathways are triggered through CD40 signal transduction. Examples include the NF-κB, MAPK, Jak3/STAT3, and PI3K/Akt pathways.

Last month to buy 1 PicoKine™ ELISA kit and get the second same PicoKine™ ELISA kit for FREE! This promotion is for inflammatory cytokines and insulin ELISA kits. Redeem your BOGO ELISA promotion soon before it ends on May 31st.

Join us at the San Diego Convention Center from May 9-13 for the American Association of Immunologists (AAI) 2019 Annual Meeting.

Cellular autofluorescence is a common problem for all fluorescence-based cell detection methods. The cells’ natural fluorescence is caused by the presence of various biological structures such as collagen, elastin, NADPH, etc., which interferes with analysis by reducing signal sensitivity and resolution of fluorochromes like FITC, GFP, and Pacific Blue.

Caspases are a family of cysteine proteases that respond in succession when activated by apoptosis stimuli, leading to proteolysis, cell disassembly, and apoptosis. The caspase cascade can be triggered by stimuli from the cell surface or the mitochondria.

Celebrate this Easter with a heart full of love, peace, and cheer. Have a blessed and wonderful Easter from all of us at Boster!

The ELISA (enzyme-linked immunosorbent assay) is recognized by scientists for its many advantages. The assay is convenient, quick, and simple to execute. ELISA’s versatility to detect peptides, proteins, antibodies, and hormones, and its ability to generate quantitative and qualitative data make it one of the most popular and powerful immunoassays available.

To best serve the research communities where suitable antibodies are hard to find, Boster provides a special discounted custom antibody production service for researchers who use non-mammalian models such as Zebrafish, Drosophila, C. elegans, and Yeast.

From now until May 31st, you can buy 1 PicoKine™ ELISA kit and get the second same PicoKine™ ELISA kit for FREE. This promotion is for inflammatory cytokines and insulin ELISA kits.

Boster will be attending 2 exciting events and we hope to see you there!

The March edition of Research Spotlight features 10 recent research discoveries from scientists whom Boster has served.

From now until May 31st, you can buy 1 PicoKine™ ELISA kit and get the second same PicoKine™ ELISA kit for FREE. This promotion is for inflammatory cytokines and insulin ELISA kits.

T cells are a category of lymphocytes that differ from other lymphocytes because of the unique T cell receptor (TCR) present on the cell surface. Together with co-receptors (CD4 for helper T cells and CD8 for cytotoxic T cells), the TCR enables T cells to detect and react to peptide antigens, which are pathogens digested by antigen presenting cells (APCs) and displayed on major histocompatibility complex (MHC) molecules.

First described in 1979, the technique of western blotting has since become one of the most commonly used analytical methods in life science research. Just last week, we received a few questions from confused researchers about weird band sizes in their western blot results

With 25+ years of experience, Boster provides PicoKine™ ELISA kits powered by proprietary signal-enhancing blocking technology. These ELISA kits can detect antigens in the pg/ml range with low background. We thoroughly validate each lot to ensure lot-to-lot consistency, reproducibility, and cross-reactivity.

Our February edition of Research Spotlight features 10 recent research discoveries from scientists whom Boster has served.

Today is World Cancer Day. Each year, organizations and people from around the world unite on February 4th to raise awareness about cancer.

As the most abundant free amino acid in the plasma, glutamine participates in a variety of biochemical processes, such as protein and lipid synthesis, cellular energy production, and nitrogen and carbon donation.

In the lab, researchers invest time and effort to optimize the sample preparation and sample staining processes of IHC. When successful, the results produce a strong and specific signal.

The January edition of Research Spotlight features 10 recent research discoveries from scientists whom Boster has served.

When you choose Boster, we guarantee product quality and timely support from our scientific experts. Our products are guaranteed to meet specifications on the datasheets. If the product does not work as stated, we will provide a refund or free replacement.

Happy New Year! As we begin 2019, what are your top goals for your lab in the new year? Try the word search below to see what you care most about this year.