Mouse recombinant IL-21 (Interleukin-21) protein, AF

Product Name

Mouse recombinant IL-21 (Interleukin-21) protein, AF

View all IL-21 recombinant proteins

SKU/Catalog Number

PROTQ9ES17-3

Size

5ug,20ug,100ug

Tag

His Tag (C-term)

Description

Interleukin-21 (IL-21) belongs to the IL-15/IL-21 family, which exerts pleiotropic immune regulations. IL-21 produced primarily by natural killer T (NKT) cells, T follicular helper (TFH) cells and TH17 cells. As a pleiotropic cytokine, IL-21 has been shown to regulate both innate and humoral immunity. It has potent inhibitory activity towards the activation and maturation of granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced dendritic cells (DCs). In B cells, IL-21 has a major role in the development of immunoglobulin responses. In T cells, it is required to facilitate the functional differentiation of several CD4+ T cell subsets. In addition, the ability of IL-21 to enhance the cytotoxic activity of both CD8+ T cells and NK cells makes it as a potential antitumor agent.

Storage & Handling

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.

Cite This Product

Mouse recombinant IL-21 (Interleukin-21) protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTQ9ES17-3)

Form

Lyophilized

Formulation

The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.

Purity

>95% as determined by SDS-PAGE.

Predicted MW

18.653kDa

Validation Images & Assay Conditions

Gene/Protein Information For IL21 (Source: Uniprot.org, NCBI)

Alternative Names

Za11 IL21 CVID11, IL-21, Za11 interleukin 21 interleukin-21

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

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