Interleukin-21 Antibodies

AND IL21 ELISA kits, Interleukin-21 Proteins

Many biological assays use antibodies to detect Interleukin-21, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-21 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-21 antibodies...

We validate the specificity of these antibodies to Interleukin-21 by testing them on tissues known to express IL21 positively and negatively. Browse below to find the IL21 antibody that suites your experiment. We have 10 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IL21 Infographic by Boster Bio

All IL21 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Mouse IL-21/Interleukin-21 ELISA Kit PicoKine®

15 Citations 7 Q&As

Mouse

ELISA

$499
Cat # EK0797
96 wells/kit, with removable strips.

IL-21 Interleukin-21 Rat Recombinant Protein

Rat

$250
Cat # PROTA3QPB9
2ug, 10ug, 1mg

IL-21 Interleukin-21 Mouse Recombinant Protein

Mouse

$250
Cat # PROTQ9ES17
2ug, 10ug, 1mg

Anti-IL-21 Antibody

Human, Mouse, Rat

ELISA, ICC, WB

$449
Cat # A00459
0.1 mg

Anti-IL-21/Il21 Antibody

Mouse, Rat

ELISA, IHC

$370
Cat # A00459-1
100 μg/vial

Human IL-21 Recombinant Protein

SDS-PAGE, Bioactivity

$293
Cat # PROTQ9HBE4
Starting from 10ug

IL21 (NM_021803) Human Over-expression Lysate

Human

$628
Cat # LS059067
100 µg

Human recombinant IL-21 (Interleukin-21) protein, AF

Human

Cell Culture

$77
Cat # PROTQ9HBE4-5
5ug,20ug,100ug

Mouse recombinant IL-21 (Interleukin-21) protein, AF

Mouse

Cell Culture

$77
Cat # PROTQ9ES17-3
5ug,20ug,100ug

Human recombinant IL-21 protein, GMP

Human

Cell Culture, ELISA

$1196
Cat # PROTQ9HBE4-6
100ug,1mg

IL21 Overview

Facts about Interleukin-21.

IL21 3D structure. Source: alphafold

Interleukin-21 (IL21)

May encourage the transition between innate and adaptive immunity. Induces the creation of IgG(1) and IgG(3) in B-cells (By similarity).

May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli.

Gene Information

Human
Gene Name:	IL21
Uniprot:	Q9HBE4
Entrez:	59067

Family

Belongs to:

IL-15/IL-21 family

Alternative Names

CVID11; IL21; IL-21; IL-21Za11interleukin-21; interleukin 21; interleukin-21 isoform; Za11

Molecular Weight

Mass (kDA):
18.653 kDA

Genomic Context


Human

Location:	4q27
Sequence:	4; NC_000004.12 (122610108..122621066, complement)

Tissue Specificity

Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.

Subcellular Localizations

Secreted.

Diseases

Autoimmune Reaction
Autoimmune Diseases
Celiac Disease
Arthritis
Diabetes Mellitus
Diabetes Mellitus, Insulin-dependent
Rheumatoid Arthritis
Dysequilibrium Syndrome
Lupus Erythematosus, Systemic
Ulcer
Neoplasms
Colitis
Autoimmunity

Ulcerative Colitis
Inflammatory Bowel Diseases
Inflammation
Intestinal Diseases
Malignant Neoplasms
Crohn Disease
Experimental Autoimmune Encephalomyelitis

Pathways

Pathogenesis
Cell Differentiation
Cell Activation
Secretion
Immunoglobulin Production
B Cell Differentiation
T Cell Activation
Immune Response
Cell Development
Cytokine Production
Germinal Center Formation
Cytokine Secretion
Plasma Cell Differentiation

B Cell Activation
Oxidative Phosphorylation
Inflammatory Response
Cell Proliferation
Endothelial Cell Activation
T Cell Homeostatic Proliferation
Immunoglobulin Secretion

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL21

References

PMID: 11081504 by Parrish-Novak J., et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.

PMID: 17673207 by Rahman M., et al. Cloning and characterization of an isoform of interleukin-21.

15 Publications of Boster Interleukin-21 Antibodies & ELISA Kits

PubMed ID: 10.7150/thno.44715, Characterization of IL-21-expressing recombinant hepatitis B virus (HBV) as a th...
PubMed ID: 10.7150/thno.35331, IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse...
PubMed ID: 10.1097/MEG.0000000000001712, Upregulation of microRNA-219-5p relieves ulcerative colitis through balancing th...
PubMed ID: 10.1039/D1FO00596K, A polysaccharide from natural Cordyceps sinensis regulates the intestinal immuni...
PubMed ID: 10.1038/srep29556, Live attenuated Salmonella displaying HIV-1 10E8 epitope on fimbriae: systemic a...
PubMed ID: 10.1021/acs.jafc.5b06177, Lactobacillus plantarum NCU116 Attenuates Cyclophosphamide-Induced Immunosuppres...
PubMed ID: 10.1016/j.fct.2020.111244, Ganoderma atrum polysaccharide ameliorates intestinal mucosal dysfunction associ...
PubMed ID: 10.1016/j.carbpol.2020.115957, Cultured Cordyceps sinensis polysaccharides modulate intestinal mucosal immunity...
PubMed ID: 10.1016/j.biopha.2018.03.066, The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis ...
PubMed ID: 10.1016/j.antiviral.2021.105076, Prior transient exposure to interleukin-21 delivered by recombinant adeno-associ...
PubMed ID: , Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of v...
PubMed ID: 33865876, Shen Z,Gao Z,Gu C,Wu J,Wang J,Zhang J,Xie Y,Liu J.Prior transient exposure to in...
PubMed ID: 27411313, Live attenuated Salmonella displaying HIV-1 10E8 epitope on fimbriae: systemic a...
PubMed ID: 29242561, Shen, Z., Yang, H., Yang, S., Wang, W., Cui, X., Zhou, X.,..., & Liu, J. (2017)....
PubMed ID: 25546013, Yu Ht, Tian D, Wang Jy, Guo Cx, Li Y, Wang X, Li D, Zhang Fm, Zhuang M, Ling H. ...

*More publications can be found for each product on its corresponding product page