Mouse recombinant 4-1BBL (4-1BB ligand) protein, AF

Product Name

Mouse recombinant 4-1BBL (4-1BB ligand) protein, AF

View all 4-1BB Ligand/TNFSF9 recombinant proteins

SKU/Catalog Number

PROTP41274

Size

5ug,20ug,100ug

Tag

His Tag (C-term)

Description

4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation. Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.

Storage & Handling

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.

Cite This Product

Mouse recombinant 4-1BBL (4-1BB ligand) protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP41274)

Form

Lyophilized

Formulation

The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.

Purity

>95% as determined by SDS-PAGE.

Predicted MW

26.625kDa

Validation Images & Assay Conditions

Gene/Protein Information For Tnfsf9 (Source: Uniprot.org, NCBI)

Alternative Names

4-1BB, 4-1BB-, 4-1BB-L, 4-1BBL, AI848817, Cd137, Cd137l, Ly6, Ly63l,tumor necrosis factor (ligand) superfamily, member 9 , Tnfsf9 TNFSF9 4-1BB-L, CD137L, TNLG5A TNF superfamily member 9 tumor necrosis factor ligand superfamily member 9|4-1BB ligand|4-1BBL|homolog of mouse 4-1BB-L|receptor 4-1BB ligand|tumor necrosis factor (ligand) superfamily, member 9|tumor necrosis factor ligand 5A|tumor necrosis factor superfamily member 9

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

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