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- Table of Contents
Facts about Tumor necrosis factor ligand superfamily member 9.
May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Human | |
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Gene Name: | TNFSF9 |
Uniprot: | P41273 |
Entrez: | 8744 |
Belongs to: |
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tumor necrosis factor family |
41BB Ligand; 4-1BB Ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L; receptor 4-1BB ligand; TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9
Mass (kDA):
26.625 kDA
Human | |
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Location: | 19p13.3 |
Sequence: | 19; NC_000019.10 (6531026..6535924) |
Expressed in brain, placenta, lung, skeletal muscle and kidney.
Membrane; Single-pass type II membrane protein.
PMID: 8088337 by Alderson M.R., et al. Molecular and biological characterization of human 4-1BB and its ligand.
PMID: 20032458 by Won E.Y., et al. The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily.