Interleukin-18 Antibodies

AND IL18 ELISA kits, Interleukin-18 Proteins

Many biological assays use antibodies to detect Interleukin-18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-18 antibodies...

We validate the specificity of these antibodies to Interleukin-18 by testing them on tissues known to express IL18 positively and negatively. Browse below to find the IL18 antibody that suites your experiment. We have 19 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IL18 Video by Boster Bio

All IL18 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Rat IL-18/IL-1F4/Interleukin-18 ELISA Kit PicoKine®

68 Citations 11 Q&As

Rat

ELISA

$399
Cat # EK0592
96 wells/kit, with removable strips.

Human IL-18/IL-1F4/Interleukin-18 ELISA Kit PicoKine®

45 Citations 9 Q&As

Human

ELISA

$499
Cat # EK0864
96 wells/kit, with removable strips.

Anti-Interleukin-18 IL18 Antibody Picoband®

4 Citations 15 Q&As

Human

$370
Cat # PA1342
100 μg/vial

Anti-Interleukin-18 IL18 Antibody Picoband®

4 Citations 16 Q&As

Human

IHC, WB

$370
Cat # PA2037
100 μg/vial

Anti-IL18 Antibody Picoband®

4 Citations 19 Q&As

Human

IF, IHC, ICC, WB

$370
Cat # PB9006
100 μg/vial

Anti-IL18 Antibody Picoband®

3 Citations 18 Q&As

Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # PB9014
100 μg/vial

Anti-IL18 Antibody Picoband®

3 Citations 15 Q&As

Mouse

$370
Cat # PB9245
100 μg/vial

Anti-Interleukin-18 IL18 Antibody Picoband®

4 Citations 5 Q&As

Mouse

ELISA, IHC, WB

$370
Cat # RP1017
100 μg/vial

Anti-Mouse IL-18 Antibody

2 Citations 14 Q&As

Mouse

IF, IHC

$699
Cat # A00124
500ug

Mouse IL-18 Recombinant Protein

Cell Culture

$360
Cat # R00124-2
5 µg/vial

Anti-IL18 Antibody Picoband®

6 Q&As

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00124-1
100 μg/vial

Anti- IL-18 Monoclonal Antibody

Mouse

$299
Cat # M00124
100μg/vial

IL18 (NM_001562) Human Recombinant Protein

$1062
Cat # PROTQ14116
20 µg

Mouse IL-18/IL-1F4 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP70380
Starting from 20ug

Mouse IL-18 ELISA Kit PicoKine®

9 Citations

Mouse

ELISA

$499
Cat # EK0433
96 wells/kit, with removable strips.

IL18 (NM_001562) Human Over-expression Lysate

Human

$628
Cat # LS003606
100 µg

Human recombinant IL-18 (Interleukin-18) protein, AF

Human

Cell Culture

$77
Cat # PROTQ14116-2
5ug,20ug,100ug,500ug,1mg

Mouse recombinant IL-18 (Interleukin-18) protein, AF

Mouse

Cell Culture

$77
Cat # PROTP70380-4
5ug,20ug,100ug,500ug,1mg

Human recombinant IL-18 protein, GMP

Human

Cell Culture, ELISA

$1479
Cat # PROTQ14116-3
100ug,1mg

IL18 Overview

Facts about Interleukin-18.

IL18 3D structure. Source: alphafold

Interleukin-18 (IL18)

A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed:14528293, PubMed:25500532).

Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed:10653850). .

Gene Information

Human
Gene Name:	IL18
Uniprot:	Q14116
Entrez:	3606

Family

Belongs to:

IL-1 family

Alternative Names

Iboctadekin; IFN-gamma-inducing factor; IGIF; IGIFIL-1 gamma; IL18; IL-18; IL-18MGC12320; IL-1F4; IL1F4iboctadekin; IL-1g; Interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); Interleukin-1 gamma; interleukin-18

Molecular Weight

Mass (kDA):
22.326 kDA

Genomic Context


Human

Location:	11q23.1
Sequence:	11; NC_000011.10 (112143251..112164104, complement)

Subcellular Localizations

Secreted.

Diseases

Inflammation
Malignant Neoplasms
Neoplasms
Arthritis
Rheumatoid Arthritis
Autoimmune Reaction
Autoimmune Diseases
Inflammatory Response
Diabetes Mellitus
Diabetes Mellitus, Insulin-dependent
Infective Disorder
Obesity
Chronic Inflammation

Carcinoma
Tissue Adhesions
Atherosclerosis
Synovitis
Melanoma
Lupus Erythematosus, Systemic
Asthma

Interacting Proteins

IL18R1

Pathways

Immune Response
Pathogenesis
Secretion
Inflammatory Response
Cell Proliferation
Cytokine Production
Sensitization
Cell Cycle
Cell Adhesion
Energy Homeostasis
Regeneration
Coagulation
Lymphocyte Activation

Chemotaxis
Angiogenesis
Cell Activation
Lung Development
Killer Activity
Mast Cell Activation
Tissue Development

PTMs

Cleavage

Glycosylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL18

References

PMID: 8666798 by Ushio S., et al. Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein.

PMID: 15326478 by Gaggero A., et al. A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing.

124 Publications of Boster Interleukin-18 Antibodies & ELISA Kits

PubMed ID: PMID:28174351, Kidney Function Improvement by Soy Milk Containing Lactobacillus plantarum A7 in...
PubMed ID: PMID:25194409, Effects of pioglitazone on blood glucose and inflammatory markers of diabetic ki...
PubMed ID: PMID:23377818, Serum 17-OH progesterone and free testosterone levels in women patients with Fam...
PubMed ID: 10.4103/aian.AIAN_515_18, Interleukin 18 Polymorphisms and its serum level in Patients with Multiple Scler...
PubMed ID: 10.3892/or.2019.7270, Emodin attenuates adenosine triphosphate‑induced pancreatic ductal cell injury...
PubMed ID: 10.3892/mmr.2018.9683, Rapamycin‑induced autophagy attenuates hormone‑imbalance‑induced chronic n...
PubMed ID: 10.3892/mmr.2015.3620, Exogenous α-calcitonin gene-related peptide attenuates lipopolysaccharide-induc...
PubMed ID: 10.3892/etm.2019.8327, Effect of pulegone on the NLPR3 inflammasome during inflammatory activation of T...
PubMed ID: 10.3390/molecules25204796, Anti-Inflammatory Property of the Essential Oil from Cinnamomum camphora (Linn.)...
PubMed ID: 10.3390/cells8080897, Parkin-Dependent Mitophagy Is Required for the Inhibition of ATF4 on NLRP3 Infla...
PubMed ID: 10.3389/fphar.2021.722907, Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Me...
PubMed ID: 10.3389/fphar.2020.603689, H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated...
PubMed ID: 10.3389/fphar.2019.01003, Berberine Ameliorates Spatial Learning Memory Impairment and Modulates Cholinerg...
PubMed ID: 10.3389/fphar.2017.00334, Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation o...
PubMed ID: 10.3389/fonc.2019.00364, Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated...
PubMed ID: 10.3389/fimmu.2021.739757, Sex-Related Differences in Innate and Adaptive Immune Responses to SARS-CoV-2
PubMed ID: 10.26355/eurrev_201908_18620, Melatonin inhibits the inflammation and apoptosis in rats with diabetic retinopa...
PubMed ID: 10.2217/bmm-2019-0124, Interleukins and miRNAs intervene in the early stages of diabetic kidney disease...
PubMed ID: 10.2147/IJN.S106912, Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NL...
PubMed ID: 10.2147/DDDT.S164324, Theaflavin alleviates inflammatory response and brain injury induced by cerebral...
PubMed ID: 10.21037/atm-19-1739, The activation of IL-17 signaling pathway promotes pyroptosis in pneumonia-induc...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page