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Product Info Summary
| SKU: | PROTO95998-4 |
|---|---|
| Size: | 5ug,20ug,100ug |
| Origin Species: | Human |
| Source: | HEK293 cell |
| Application: | Cell Culture |
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Product info
Product Name
Human recombinant IL-18BP (Interleukin-18-binding protein) protein, AF
View all IL18BP recombinant proteins
SKU/Catalog Number
PROTO95998-4
Size
5ug,20ug,100ug
Tag
His Tag (C-term)
Description
IL18BP, specifically binds to IL-18, suppressing its activity. IL18BP lacks a transmembrane domain and is prominently expressed in the heart, lung, placenta, and spleen. Additionally, IL18BP regulates the early TH1 cytokine response by reducing IFN-gamma production, moderating T-helper type 1 immune responses.
Storage & Handling
Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.
Cite This Product
Human recombinant IL-18BP (Interleukin-18-binding protein) protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTO95998-4)
Form
Lyophilized
Formulation
The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
Purity
>95% as determined by SDS-PAGE.
Predicted MW
21.099kDa
Molecular weight
The protein has a calculated MW of 18.44 kDa. The protein migrates as 35 kDa under reducing condition (SDS-PAGE analysis).
Activity
Testing in process
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Amino Acid Sequence
A DNA sequence encoding Human IL-18BP Protein(#O95998) (Met1-Gly194) was expressed with polyhistidine tag at the C-terminus.
Reconstitution
Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.
Assay dilution & Images
Validation Images & Assay Conditions
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SDS- PAGE analysis of recombinant human IL-18BP
Protein Target Info & Infographic
Gene/Protein Information For IL18BP (Source: Uniprot.org, NCBI)
Gene Name
IL18BP
Full Name
Interleukin-18-binding protein
Weight
21.099kDa
Alternative Names
Tadekinig-alfa, IL18BP IL18BP FVHa, IL18BP interleukin 18 binding protein interleukin-18-binding protein|MC51L-53L-54L homolog gene product|tadekinig-alfa
*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".For more info on IL18BP, check out the IL18BP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL18BP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].
Specific Publications For Human recombinant IL-18BP (Interleukin-18-binding protein) protein, AF (PROTO95998-4)
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