Human recombinant BMP-10 (Bone morphogenetic protein-10) protein, AF

BMP-10 protein, Human

Bone Morphogenetic Protein-10 (BMP-10) is an extracellular multifunctional signaling cytokine that is also a member of the TGFβ family. BMP-10 can bind with TGFβ receptor and is involved in SMAD protein signal transduction. The functions related to bone generation can induce bone and cartilage formation. Different from other family members, BMP-10 is a novel protein involved in the heart's trabeculation.

Product Info Summary

SKU: PROTO95393-2
Size: 5ug,20ug,100ug
Origin Species: Human
Source: Escherichia coli
Application: Cell Culture

Product Name

Human recombinant BMP-10 (Bone morphogenetic protein-10) protein, AF

View all BMP-10 recombinant proteins

SKU/Catalog Number

PROTO95393-2

Size

5ug,20ug,100ug

Tag

His Tag (C-term)

Description

Bone Morphogenetic Protein-10 (BMP-10) is an extracellular multifunctional signaling cytokine that is also a member of the TGFβ family. BMP-10 can bind with TGFβ receptor and is involved in SMAD protein signal transduction. The functions related to bone generation can induce bone and cartilage formation. Different from other family members, BMP-10 is a novel protein involved in the heart's trabeculation.

Storage & Handling

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.

Cite This Product

Human recombinant BMP-10 (Bone morphogenetic protein-10) protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTO95393-2)

Form

Lyophilized

Formulation

The protein was lyophilized from a 0.2 μm filtered solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 3.5. If you have any concerns or special requirements, please confirm with us.

Purity

>98% as determined by SDS-PAGE.

Predicted MW

47.888kDa

Molecular weight

The protein has a calculated MW of 13.10 kDa. The protein migrates as 16 kDa under reducing condition (SDS-PAGE analysis).

Activity

Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED₅₀ for this effect is 1.7-2.1 ng/mL.

Endotoxin

<0.1 EU per 1 μg of the protein by the LAL method.

Amino Acid Sequence

MNAKGNYCKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLEPISILYLDKGVVTYKFKYEGMAVSECGCR with polyhistidine tag at the C-terminus.

Reconstitution

Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Validation Images & Assay Conditions

Gene/Protein Information For BMP10 (Source: Uniprot.org, NCBI)

Gene Name

BMP10

Full Name

Bone morphogenetic protein 10

Weight

47.888kDa

Superfamily

TGF-beta family

Alternative Names

BMP10; BMP-10; bone morphogenetic protein 10; MGC126783 Bmp10|b2b2711C, b2b2711Clo|bone morphogenetic protein 10|bone morphogenetic protein 10|BMP-10

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

For more info on BMP10, check out the BMP10 Infographic

BMP10 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for BMP10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].

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Size

Total: $77

SKU:PROTO95393-2

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