Calumenin Antibodies

AND CALU ELISA kits, Calumenin Proteins

Many biological assays use antibodies to detect Calumenin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calumenin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calumenin antibodies...

We validate the specificity of these antibodies to Calumenin by testing them on tissues known to express CALU positively and negatively. Browse below to find the CALU antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CALU Infographic by Boster Bio

All CALU Products

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Product

Figures

Specificity

Applications

Price

Anti-Calumenin Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A03193
100ul

Anti-Calumenin (C-terminus) monoclonal Antibody

Human, Mouse

$482
Cat # M03193
100ul

Calumenin (CALU) (NM_001219) Human Recombinant Protein

$813
Cat # PROTO43852
20 µg

Anti-Calumenin Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M03193-1
100 μl/vial

Calumenin (CALU) (NM_001219) Human Over-expression Lysate

Human

$628
Cat # LS000813
100 µg

CALU Overview

Facts about Calumenin.

CALU 3D structure. Source: alphafold

Calumenin (CALU)

Involved in regulation of vitamin K-dependent carboxylation of numerous N-terminal glutamate residues. Appears to inhibit gamma-carboxylase GGCX.

Binds 7 calcium ions with a low affinity (By similarity). .

Gene Information

Human
Gene Name:	CALU
Uniprot:	O43852
Entrez:	813

Family

Belongs to:

CREC family

Alternative Names

calumenin; crocalbin; crocalbin-like protein; FLJ90608; IEF SSP 9302; multiple EF-hand protein

Molecular Weight

Mass (kDA):
37.107 kDA

Genomic Context


Human

Location:	7q32.1
Sequence:	7; NC_000007.14 (128739359..128773400)

Tissue Specificity

Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.

Subcellular Localizations

Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Diseases

Neoplasms
Malignant Neoplasms
Hemorrhage
Skin Callus
Cerebrovascular Accident
Thrombosis
Neoplasm Metastasis
Bleeding Tendency
Malignant Neoplasm Of Lung
Lung Neoplasms
Atherosclerosis

Malignant Neoplasm Of Breast
Pulmonary Embolism
Glioma
Thromboembolism
Neoplasm Invasiveness
Carcinoma

Pathways

Localization
Secretory Pathway
Coagulation
Cell Cycle
Cytokinesis
Secretion
Transport
Response To Vitamin K
Blood Coagulation
Intracellular Transport
Photosynthesis
Response To Vitamin

Cell Division
Fermentation
Translation
Cell Growth
Wound Healing
Pathogenesis

PTMs

Gamma-carboxylation
Carboxylation

Reduction
Deglycosylation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CALU

References

PMID: 9675259 by Vorum H., et al. Molecular cloning of a cDNA encoding human calumenin, expression in Escherichia coli and analysis of its Ca2+-binding activity.

PMID: 9598325 by Yabe D., et al. Human calumenin gene (CALU): cDNA isolation and chromosomal mapping to 7q32.