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Ptprq Antibodies
AND Ptprq ELISA kits, Ptprq Proteins
Many biological assays use antibodies to detect Ptprq, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ptprq in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ptprq antibodies...
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Ptprq Overview
Facts about Phosphatidylinositol phosphatase PTPRQ.
Phosphatidylinositol phosphatase PTPRQ (Ptprq)
May act by regulating the amount of phosphatidylinositol 4,5-bisphosphate (PIP2) level in the basal area of hair bundles. Can dephosphorylate a broad assortment of phosphatidylinositol phosphates, including phosphatidylinositol 3,4,5-trisphosphate and many phosphatidylinositol monophosphates and diphosphates.
Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has reduced tyrosine-protein phosphatase activitynonetheless, the relevance of these activity in vivo is unclear.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Ptprq |
| Uniprot: | P0C5E4 |
| Entrez: | 237523 |
Family
| Belongs to: |
|---|
| protein-tyrosine phosphatase family |
Alternative Names
Phosphatidylinositol phosphatase PTPRQ
Molecular Weight
Mass (kDA):
256.785 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 10 D1|10 55.97 cM |
| Sequence: | 10; |
Tissue Specificity
In the inner ear of the early postnatal mouse, it is present in hair bundles in the cochlea and in the vestibule. Restricted to the hair bundles and not detected in any other cell type within the inner ear. Restricted to the basal region of the hair bundle (at protein level).
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ptprq
bosterbio.com/bosterbio-gene-info-cards/Ptprq
References
PMID: 14534255 by Goodyear R.J., et al. A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles.