This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Coagulation factor VII.
Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis.
Human | |
---|---|
Gene Name: | F7 |
Uniprot: | P08709 |
Entrez: | 2155 |
Belongs to: |
---|
peptidase S1 family |
coagulation factor VII (serum prothrombin conversion accelerator); Coagulation Factor VII; EC 3.4.21; EC 3.4.21.21; Eptacog alfa; F7; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
Mass (kDA):
51.594 kDA
Human | |
---|---|
Location: | 13q34 |
Sequence: | 13; NC_000013.11 (113105773..113120685) |
Plasma.
Secreted.
PMID: 3486420 by Hagen F.S., et al. Characterization of a cDNA coding for human factor VII.
PMID: 3037537 by O'Hara P.J., et al. Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation.