CDHR1 Antibodies

AND CDHR1 ELISA kits, CDHR1 Proteins

Many biological assays use antibodies to detect CDHR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDHR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDHR1 antibodies...

We validate the specificity of these antibodies to CDHR1 by testing them on tissues known to express CDHR1 positively and negatively. Browse below to find the CDHR1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDHR1 Infographic by Boster Bio

All CDHR1 Products

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Anti-Zebrafish cdhr1a Antibody

Zebrafish

$470
Cat # DZ07988
200 μl/vial

CDHR1 Overview

Facts about Cadherin-related family member 1.

CDHR1 3D structure. Source: alphafold

Cadherin-related family member 1 (CDHR1)

Potential calcium-dependent cell-adhesion protein. Might be required for the structural integrity of the outer segment (OS) of photoreceptor cells (By similarity).

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Gene Information

Human
Gene Name:	CDHR1
Uniprot:	Q96JP9
Entrez:	92211

Family

Belongs to:

No superfamily

Alternative Names

cadherin-related family member 1; CORD15; KIAA1775DKFZp434A132; PCDH21MT-protocadherin; Photoreceptor cadherin; prCAD; PRCADprotocadherin-21; protocadherin 21; Protocadherin-21

Molecular Weight

Mass (kDA):
93.595 kDA

Genomic Context


Human

Location:	10q23.1
Sequence:	10; NC_000010.11 (84194537..84219621)

Subcellular Localizations

Cell membrane; Single-pass membrane protein. Localized at the junction between the inner and outer segments of rod and cone photoreceptors cells. Confined to the base of the OS. Localized on the edges of nascent evaginating disks on the side of the OS opposite the connecting cilium. Expressed at postnatal day 2 at the apical tip of the rod photoreceptor cells, the site of the developing OS. Colocalized with rhodopsin between postnatal days 2 and 9 at the base of the growing OS region (By similarity).

Diseases

Retinal Degeneration
Blind Vision
Dystrophy
Retinal Dystrophies
Retinitis Pigmentosa
Night Blindness
Age Related Macular Degeneration
Amaurosis
Macule
Atrophy
Protrusion
Color Vision Defect

Fetal Membranes, Premature Rupture
Usher Syndrome, Type I
Epithelial Atrophy
Usher Syndrome
Leber Congenital Amaurosis
Maculopathy

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDHR1

References

PMID: 11597768 by Nakajima D., et al. Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.

PMID: 18654668 by Yang Z., et al. Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.