ZP3 Antibodies

AND ZP3 ELISA kits, ZP3 Proteins

Many biological assays use antibodies to detect ZP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZP3 antibodies...

We validate the specificity of these antibodies to ZP3 by testing them on tissues known to express ZP3 positively and negatively. Browse below to find the ZP3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZP3 Infographic by Boster Bio

All ZP3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ZP3 Antibody Picoband®

15 Q&As

Human

$370
Cat # A03543-1
100 μg/vial

ZP3 (NM_007155) Human Over-expression Lysate

Human

$628
Cat # LS007784
100 µg

ZP3 Overview

Facts about Zona pellucida sperm-binding protein 3.

ZP3 3D structure. Source: alphafold

Zona pellucida sperm-binding protein 3 (ZP3)

The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of a few glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.

Gene Information

Human
Gene Name:	ZP3
Uniprot:	P21754
Entrez:	7784

Family

Belongs to:

ZP domain family

Alternative Names

zona pellucida glycoprotein 3 (sperm receptor)

Molecular Weight

Mass (kDA):
47.018 kDA

Genomic Context


Human

Location:	7q11.23
Sequence:	7; NC_000007.14 (76397522..76442069)

Tissue Specificity

Oocytes.

Subcellular Localizations

[Processed zona pellucida sperm-binding protein 3]: Secreted, extracellular space, extracellular matrix. Located in oocyte zona pellucida.; Cell membrane; Single-pass type I membrane protein.

Diseases

Infertility
Autoimmune Reaction
Tissue Adhesions
Autoimmune Diseases
Ovarian Diseases
Female Infertility
Pertussis
Male Infertility
Disorder Of Endocrine Ovary
Diphtheria
Cytomegalovirus Infections
Inflammation

Ovarian Failure, Premature
Premature Menopause
Autoimmunity
Classical Galactosemia
Embryonal Carcinoma
Carcinoma

Interacting Proteins

Pathways

Fertilization
Acrosome Reaction
Exocytosis
Oogenesis
Glycosylation
Secretion
Localization
Sperm-egg Recognition
Oocyte Maturation
Ovulation
Immune Response
Mating
Oocyte Growth

Translation
Oocyte Development
Pathogenesis
Metaphase
Sperm Capacitation
Proteolysis
Cortical Granule Exocytosis

PTMs

Glycosylation
Cleavage
Deglycosylation
Phosphorylation
Biotinylation
Reduction

Amination
Acetylation
Methylation
Ribosylation
Ubiquitination
Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZP3

References

PMID: 2385582 by Chamberlin M.E., et al. Human homolog of the mouse sperm receptor.

PMID: 1478648 by van Duin M., et al. Cloning and characterization of the human sperm receptor ligand ZP3: evidence for a second polymorphic allele with a different frequency in the Caucasian and Japanese populations.