Zp1 Antibodies

Zona pellucida sperm-binding protein 1 (Zp1)

The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of a few glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.

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Gene Information

Mouse
Gene Name:	Zp1
Uniprot:	Q62005
Entrez:	22786

Family

Belongs to:
ZP domain family

Alternative Names

KIAA0395TIX1; triple homeobox 1; Triple homeobox protein 1; Zinc finger and homeodomain protein 3; zinc fingers and homeoboxes 3; zinc fingers and homeoboxes protein 3

Molecular Weight

Mass (kDA):
68.723 kDA

Genomic Context

Mouse
Location:	19 A|19 7.36 cM
Sequence:	19;

Tissue Specificity

Oocytes.

Diseases

• Infertility
• Female Infertility
• Diphtheria
• Pertussis
• Chimera Disorder
• Tissue Adhesions
• Sterility
• Disorder Of Endocrine Ovary
• Autoimmunity
• Insulinoma
• Endometriosis, Site Unspecified
• Malignant Neoplasms

• Neoplasms
• Cytomegalovirus Infections
• Testicular Diseases
• Headache
• Pancreatic Neoplasm
• Malignant Neoplasm Of Ovary

Pathways

• Fertilization
• Acrosome Reaction
• Oogenesis
• Exocytosis
• Secretion
• Sperm-egg Recognition
• Glycosylation
• Localization
• Ovulation
• Proteolysis
• Mating
• Oocyte Growth
• Oocyte Development

• Cortical Granule Exocytosis
• Translation
• Transport
• Immune Response
• Spermatogenesis
• Blastocyst Formation
• Cell Differentiation

PTMs

• Cleavage
• Glycosylation
• Methylation
• Biotinylation

• Reduction
• Oxidation
• Deglycosylation
• Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Zp1

Boster Bio - Best Uses Of The ZP1 Marker

Look no further if your goal is to find a high-quality primary antibody against the ZP1 marker. Boster offers highly-validated antibody that has been used in numerous studies for more than 25 years. Boster antibodies are characterized by their high affinity and have been validated using Western Blotting, Immunohistochemistry, and ELISA. Find out how Boster antibody can help you improve your research.

Anti-KHDRBS2

The ZP1 markers are a useful tool for detecting a variety protein targets in a wide range applications. It has been used successfully in many types of biochemical and molecular research studies. Boster has provided high-affinity primary antibodies that are well-validated for use in Western Blotting, Immunohistochemistry, and ELISA. These antibodies have been used for over 25 years by researchers.

The ZP1 protein was purified by affinity and MALDITOF/MS/MS. Western blotting confirmed both the presence of hZP1 (and hZP4) in affinity purified, hZP2 (and hZP3) samples. Both hZP1 as well as hZP4 could be detected by gel electrophoresis or western blotting.

Anti-Bax

Numerous studies have shown a decreased expression of ZP1 in mice without functional mRNA. This could be due to differences in transcription factor binding sites or promoters. However, studies of turkeys have also been reported. The ZP1 protein marker is a novel antibody that targets a specific gene. It has many potential applications.

Anti-S4

The Boster Bio anti-KHDRBS2 antibody reacts with Human in Western Blotting and Immunohistochemistry. It has been extensively tested both in immunohistochemistry, and Western Blotting. The antibody is supplied as a 100ul Liquid solution. It is suitable for ELISA, IHC, and immunohistochemistry. There are many dilution options available for this product, including dilute solution, aliquots, as well as swabs.

Purified hZP1 glycoproteins were characterized by western blotting and MALDI-TOF-MS/MS. After affinity chromatography, a flow-through fraction contained both hZP1 as well as hZP4 proteins. The purified proteins were not fractionated further to remove hZP1 because it contained a large concentration of hZP4. Further, western blotting confirmed that both hZP1 as well as hZP4 are present.