Zinc finger protein 750 Antibodies

AND ZNF750 ELISA kits, Zinc finger protein 750 Proteins

Many biological assays use antibodies to detect Zinc finger protein 750, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein 750 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein 750 antibodies...

We validate the specificity of these antibodies to Zinc finger protein 750 by testing them on tissues known to express ZNF750 positively and negatively. Browse below to find the ZNF750 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNF750 Infographic by Boster Bio

All ZNF750 Products

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Price

Anti-ZN750 ZNF750 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08743
100ul

ZNF750 (NM_024702) Human Over-expression Lysate

Human

$960
Cat # LS079755
100 µg

ZNF750 Overview

Facts about Zinc finger protein 750.

ZNF750 3D structure. Source: alphafold

Zinc finger protein 750 (ZNF750)

Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes.

Specifically binds to the promoter of KLF4 and promotes its expression. .

Gene Information

Human
Gene Name:	ZNF750
Uniprot:	Q32MQ0
Entrez:	79755

Family

Belongs to:

No superfamily

Alternative Names

FLJ13841; FLJ51362; MGC125667; MGC125668; protein ZNF750; ZFP750; zinc finger protein 750

Molecular Weight

Mass (kDA):
77.361 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (82829434..82840022, complement)

Tissue Specificity

Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.

Subcellular Localizations

Nucleus.

Diseases

Dermatitis
Psoriasis
Dermatologic Disorders
Seborrheic Dermatitis
Parakeratosis
Dermatitis, Atopic
Cleft Palate
Ichthyoses
Eye Abnormalities

Ectodermal Dysplasia
Psoriasiform Dermatitis
Cleft Lip
Hay-wells Syndrome Of Ectodermal Dysplasia

Interacting Proteins

CTBP2

Pathways

Keratinocyte Proliferation
Keratinocyte Differentiation
Localization

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF750

References

PMID: 16751772 by Birnbaum R.Y., et al. Seborrhea-like dermatitis with psoriasiform elements caused by a mutation in ZNF750, encoding a putative C2H2 zinc finger protein.

PMID: 22364861 by Sen G.L., et al. ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation.