Zinc finger protein 281 Antibodies

AND ZNF281 ELISA kits, Zinc finger protein 281 Proteins

Many biological assays use antibodies to detect Zinc finger protein 281, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein 281 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein 281 antibodies...

We validate the specificity of these antibodies to Zinc finger protein 281 by testing them on tissues known to express ZNF281 positively and negatively. Browse below to find the ZNF281 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNF281 Infographic by Boster Bio

All ZNF281 Products

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Anti-ZFP281 ZNF281 Antibody

Human, Mouse

ELISA, IF, WB

$449
Cat # A07538
0.1 mg

ZNF281 (NM_012482) Human Over-expression Lysate

Human

$628
Cat # LS023528
100 µg

ZNF281 Overview

Facts about Zinc finger protein 281.

ZNF281 3D structure. Source: alphafold

Zinc finger protein 281 (ZNF281)

Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and functions by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones.

Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM.

Gene Information

Human
Gene Name:	ZNF281
Uniprot:	Q9Y2X9
Entrez:	23528

Family

Belongs to:

krueppel C2H2-type zinc-finger protein family

Alternative Names

FLJ20557; GZP1; ZBP-99; zinc finger protein 416; ZNF281; ZNP-99

Molecular Weight

Mass (kDA):
96.915 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (200404951..200410036, complement)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasm Of Prostate
Adenocarcinoma
Gastric Adenocarcinoma
Neoplasm Metastasis
Prostatic Neoplasms
Malignant Neoplasms

Adenocarcinoma Of Colon
Hyperplasia

Pathways

Cell Division
Cell Proliferation
Localization

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF281

References

PMID: 10448078 by Law D.J., et al. ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression.

PMID: 10405178 by Lisowsky T., et al. Identification of human GC-box-binding zinc finger protein, a new Krueppel-like zinc finger protein, by the yeast one-hybrid screening with a GC-rich target sequence.