Zinc finger protein with KRAB and SCAN domains 3 (Zkscan3)

Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function like MAP1LC3B, ULK1 or WIPI2.

Associates with chromatin in the ITGB4 and VEGF promoters (By similarity). .