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- Table of Contents
Facts about Zinc finger protein 42.
Involved in the reprogramming of X-chromosome inactivation during the Purchase of pluripotency.
Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST.Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal.
Mouse | |
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Gene Name: | Zfp42 |
Uniprot: | P22227 |
Entrez: | 22702 |
Belongs to: |
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krueppel C2H2-type zinc-finger protein family |
FLJ20086; KIAA1584; MGC21637; MGC61687; Rex1; Rex-1; SUHW4; Suppressor of hairy wing homolog 4; ZFP42; zinc finger protein 280D; Zinc finger protein 634; ZNF634suppressor of hairy wing homolog 4 (Drosophila)
Mass (kDA):
32.398 kDA
Mouse | |
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Location: | 8 A4|8 23.89 cM |
Sequence: | 8; |
Restricted to testis, to germ cells in the early stages of spermatogenesis. Not expressed in spermatids, nor spermatozoa. Expressed in embryonic stem (ES) cells.
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PMID: 2511439 by Hosler B.A., et al. Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells.
PMID: 8474450 by Hosler B.A., et al. An octamer motif contributes to the expression of the retinoic acid- regulated zinc finger gene Rex-1 (Zfp-42) in F9 teratocarcinoma cells.