ZFAND5 Antibodies

AND ZFAND5 ELISA kits, ZFAND5 Proteins

Many biological assays use antibodies to detect ZFAND5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZFAND5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZFAND5 antibodies...

We validate the specificity of these antibodies to ZFAND5 by testing them on tissues known to express ZFAND5 positively and negatively. Browse below to find the ZFAND5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZFAND5 Infographic by Boster Bio

All ZFAND5 Products

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Product

Figures

Specificity

Applications

Price

ZFAND5 (NM_006007) Human Recombinant Protein

$813
Cat # PROTO76080
20 µg

Anti-ZFAND5 Mouse Monoclonal Antibody [Clone ID: OTI5H8]

Human, Mouse, Rat

IHC, WB

$523
Cat # M11963
100 µl

ZFAND5 (NM_001102420) Human Over-expression Lysate

Human

$628
Cat # LS007763
100 µg

ZFAND5 Overview

Facts about AN1-type zinc finger protein 5.

ZFAND5 3D structure. Source: alphafold

AN1-type zinc finger protein 5 (ZFAND5)

Involved in protein degradation via the ubiquitin- proteasome system. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy.

Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA.

Gene Information

Human
Gene Name:	ZFAND5
Uniprot:	O76080
Entrez:	7763

Family

Belongs to:

No superfamily

Alternative Names

Zinc finger A20 domain-containing protein 2; Zinc finger protein 216ZA20D2; zinc finger, AN1-type domain 5; ZNF216A20 domain containing 2

Molecular Weight

Mass (kDA):
23.132 kDA

Genomic Context


Human

Location:	9q21.13
Sequence:	9; NC_000009.12 (72351413..72365208, complement)

Tissue Specificity

Highly expressed in skeletal muscle. Expressed in fetal cochlea. Also expressed in infant brain, fetal heart, pancreatic islet, melanocyte, pineal gland, placenta, corneal stroma, and parathyroid tumor. Weakly expressed or undetectable in adult brain, heart, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. Expressed in rhabdomyosarcoma RD cells (at protein level).

Subcellular Localizations

Cytoplasm.

Diseases

Complete Hearing Loss

Interacting Proteins

Pathways

Osteoclast Differentiation
Bone Remodeling

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZFAND5

References

PMID: 9758550 by Scott D.A., et al. Identification and mutation analysis of a cochlear-expressed, zinc finger protein gene at the DFNB7/11 and dn hearing-loss loci on human chromosome 9q and mouse chromosome 19.

PMID: 14754897 by Huang J., et al. ZNF216 is an A20-like and IkappaB kinase gamma-interacting inhibitor of NFkappaB activation.