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- Table of Contents
Facts about Palmitoyltransferase ZDHHC7.
Palmitoylates SNAP25 and DLG4/PSD95 (By similarity). Palmitoylates sex steroid hormone receptors, such as ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane and their function in rapid intracellular signaling upon binding of sexual hormones (PubMed:22031296).
Human | |
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Gene Name: | ZDHHC7 |
Uniprot: | Q9NXF8 |
Entrez: | 55625 |
Belongs to: |
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DHHC palmitoyltransferase family |
EC 2.3.1; EC 2.3.1.-; FLJ10792; FLJ20279; palmitoyltransferase ZDHHC7; Sertoli cell gene with zinc finger domain- and #946; SERZ1; SERZ-B; Zinc finger DHHC domain-containing protein 7; Zinc finger protein 370; zinc finger, DHHC domain containing 7; zinc finger, DHHC-type containing 7; ZNF370DHHC-7
Mass (kDA):
35.14 kDA
Human | |
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Location: | 16q24.1 |
Sequence: | 16; NC_000016.10 (84974175..85011535, complement) |
Golgi apparatus membrane; Multi-pass membrane protein.
PMID: 22031296 by Pedram A., et al. DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors.
PMID: 28196865 by Aramsangtienchai P., et al. S-Palmitoylation of Junctional Adhesion Molecule C Regulates Its Tight Junction Localization and Cell Migration.