ZDHHC6 Antibodies

AND ZDHHC6 ELISA kits, ZDHHC6 Proteins

Many biological assays use antibodies to detect ZDHHC6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZDHHC6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZDHHC6 antibodies...

We validate the specificity of these antibodies to ZDHHC6 by testing them on tissues known to express ZDHHC6 positively and negatively. Browse below to find the ZDHHC6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZDHHC6 Infographic by Boster Bio

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ZDHHC6 (NM_022494) Human Over-expression Lysate

Human

$628
Cat # LS064429
100 µg

ZDHHC6 Overview

Facts about Palmitoyltransferase ZDHHC6.

ZDHHC6 3D structure. Source: alphafold

Palmitoyltransferase ZDHHC6 (ZDHHC6)

Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC (PubMed:22314232, PubMed:22728137, PubMed:25368151, PubMed:28826475). Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins (PubMed:22314232).

Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum (PubMed:22728137). Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to modulate ITPR1 stability and function (PubMed:25368151).

Gene Information

Human
Gene Name:	ZDHHC6
Uniprot:	Q9H6R6
Entrez:	64429

Family

Belongs to:

DHHC palmitoyltransferase family

Alternative Names

DHHC-6; EC 2.3.1; EC 2.3.1.-; FLJ21952; Transmembrane protein H4; Zinc finger DHHC domain-containing protein 6; Zinc finger protein 376; zinc finger, DHHC domain containing 6; zinc finger, DHHC-type containing 6; ZNF376probable palmitoyltransferase ZDHHC6

Molecular Weight

Mass (kDA):
47.663 kDA

Genomic Context


Human

Location:	10q25.2
Sequence:	10; NC_000010.11 (112424411..112447603, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. When not palmitoylated, accumulates to dot-like structures in the endoplasmic reticulum (PubMed:28826475).

PTMs

Lipoprotein

Palmitate

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZDHHC6

References

PMID: 21926431 by Gorleku O.A., et al. Endoplasmic reticulum localization of DHHC palmitoyltransferases mediated by lysine-based sorting signals.

PMID: 22314232 by Lakkaraju A.K., et al. Palmitoylated calnexin is a key component of the ribosome-translocon complex.