ZC3H13 Antibodies

AND ZC3H13 ELISA kits, ZC3H13 Proteins

Many biological assays use antibodies to detect ZC3H13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZC3H13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZC3H13 antibodies...

We validate the specificity of these antibodies to ZC3H13 by testing them on tissues known to express ZC3H13 positively and negatively. Browse below to find the ZC3H13 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZC3H13 Infographic by Boster Bio

All ZC3H13 Products

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Anti-ZC3H13 Antibody

Human

$360
Cat # A11022
100 µl

Anti-ZC3H13 Antibody

7 Q&As

Human, Mouse

$399
Cat # A11022-1
100μl

ZC3H13 Overview

Facts about Zinc finger CCCH domain-containing protein 13.

ZC3H13 3D structure. Source: alphafold

Zinc finger CCCH domain-containing protein 13 (ZC3H13)

Associated element of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification which plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29507755). Acts as a key regulator of m6A methylation by encouraging m6A methylation of mRNAs at the 3'- UTR (By similarity).

Controls embryonic stem cells (ESCs) pluripotency via its role in m6A methylation (By similarity). From the WMM complex, anchors component of the MACOM subcomplex in the nucleus (By similarity).

Gene Information

Human
Gene Name:	ZC3H13
Uniprot:	Q5T200
Entrez:	23091

Family

Belongs to:

ZC3H13 family

Alternative Names

FLJ35669; KIAA0853DKFZp434D1812; zinc finger CCCH domain-containing protein 13; zinc finger CCCH-type containing 13

Molecular Weight

Mass (kDA):
196.635 kDA

Genomic Context


Human

Location:	13q14.13
Sequence:	13; NC_000013.11 (45954465..46052794, complement)

Subcellular Localizations

Nucleus speckle. Nucleus, nucleoplasm.

Diseases

Stomach Neoplasms
Mutation, Out-of-frame
High-frequency Microsatellite Instability
Malignant Paraganglionic Neoplasm
Blast Phase
Microsatellite Instability
Autoimmune Diseases
Thrombocythemia, Essential
Malignant Neoplasm Of Stomach
Autoimmune Reaction
Malignant Neoplasms

Colorectal Neoplasms
Sequence Inversion
Colorectal Cancer
Low-frequency Microsatellite Instability
Thrombocytosis

Interacting Proteins

SCHIP1

Pathways

Cell Proliferation
Cell Cycle
Pathogenesis
Rna Interference

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZC3H13

References

PMID: 24100041 by Horiuchi K., et al. Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.

PMID: 29507755 by Yue Y., et al. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation.