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- Table of Contents
Facts about Probable ribonuclease ZC3H12D.
In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560). Serve as a tumor suppressor in certain leukemia cells (By similarity).
Mouse | |
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Gene Name: | Zc3h12d |
Uniprot: | Q8BIY3 |
Entrez: | 237256 |
Belongs to: |
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ZC3H12 family |
C6orf95; FLJ46041; MCP-induced protein 4; p34; TFL; transformed follicular lymphoma; tumor suppressor TFL; zinc finger CCCH-type containing 12D
Mass (kDA):
59.34 kDA
Mouse | |
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Location: | 10|10 A1 |
Sequence: | 10; |
Expressed at low levels in bone marrow derived macrophages.
PMID: 18178554 by Liang J., et al. A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages.
PMID: 26134560 by Huang S., et al. Monocyte chemotactic protein-induced protein 1 and 4 form a complex but act independently in regulation of interleukin-6 mRNA degradation.