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- Table of Contents
Facts about Zinc finger and BTB domain-containing protein 18.
Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'- [AC]ACATCTG[GT][AC]-3' that contains the E box center, and functions by recruiting chromatin remodeling multiprotein complexes.
Human | |
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Gene Name: | ZBTB18 |
Uniprot: | Q99592 |
Entrez: | 10472 |
Belongs to: |
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krueppel C2H2-type zinc-finger protein family |
Zinc finger and BTB domain-containing protein 18
Mass (kDA):
58.354 kDA
Human | |
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Location: | 1q44 |
Sequence: | 1; NC_000001.11 (244048939..244057476) |
Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.
Nucleus. Associates with condensed chromatin.
PMID: 7633419 by Becker K.G., et al. Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain.
PMID: 9756912 by Aoki K., et al. RP58 associates with condensed chromatin and mediates a sequence- specific transcriptional repression.