ZBTB16 Antibodies

AND ZBTB16 ELISA kits, ZBTB16 Proteins

Many biological assays use antibodies to detect ZBTB16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZBTB16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZBTB16 antibodies...

We validate the specificity of these antibodies to ZBTB16 by testing them on tissues known to express ZBTB16 positively and negatively. Browse below to find the ZBTB16 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZBTB16 Infographic by Boster Bio

All ZBTB16 Products

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Product

Figures

Specificity

Applications

Price

Anti-Plzf/ZBTB16 Antibody Picoband®

7 Q&As

Human, Rat

$370
Cat # PB9969
100 μg/vial

Anti-PLZF ZBTB16 Monoclonal Antibody

Human

ELISA, IF, WB

$380
Cat # M00817
100ul

Anti-Plzf/ZBTB16 Antibody Picoband®

1 Citations

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A00817-1
100 μg/vial

Plzf (ZBTB16) (NM_006006) Human Over-expression Lysate

Human

$628
Cat # LS007704
100 µg

ZBTB16 Overview

Facts about Zinc finger and BTB domain-containing protein 16.

Zinc finger and BTB domain-containing protein 16 (ZBTB16)

Acts as a transcriptional repressor (PubMed:24359566). May play a role in myeloid maturation and in the development and/or upkeep of other differentiated tissues.

Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312). .

Gene Information

Human
Gene Name:	ZBTB16
Uniprot:	Q05516
Entrez:	7704

Family

Belongs to:

krueppel C2H2-type zinc-finger protein family

Alternative Names

PLZF; PLZFzinc finger and BTB domain-containing protein 16; ZBTB16; zinc finger and BTB domain containing 16; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); Zinc finger protein 145; Zinc finger protein PLZF; ZNF145; ZNF145Promyelocytic leukemia zinc finger protein

Molecular Weight

Mass (kDA):
74.274 kDA

Genomic Context


Human

Location:	11q23.2
Sequence:	11; NC_000011.10 (114059576..114256770)

Tissue Specificity

Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Subcellular Localizations

Nucleus. Nucleus, nuclear body.

Diseases

Leukemia
Acute Promyelocytic Leukemia
Malignant Neoplasms
Neoplasms
Chromosomal Translocation
Myeloid Leukemia
Cell Transformation, Neoplastic
Leukemia, Myelocytic, Acute
Leukemogenesis
Growth Retardation
Malignant Paraganglionic Neoplasm
Melanoma

Lymphoma
Chimera Disorder
Tissue Adhesions
Anemia
Infertility
Acute Lymphocytic Leukemia
L1 Acute Lymphoblastic Leukemia

Interacting Proteins

CEP70
COG6
EEF1A1
Gne
GOLGA2

Hoxa1
IL6
KRT40
LDOC1
PML

TAB2
TRAF1
TRAF2
TRIM27
TRIM54

VTA1

Pathways

Cell Cycle
Pathogenesis
Cell Growth
Spermatogenesis
Localization
Cell Development
Cell Proliferation
Chromatin Remodeling
Regeneration
Cell Cycle Arrest
Cell Death
Stem Cell Maintenance
Ossification

Nuclear Export
Limb Development
Cell Differentiation
Oncogenesis
Immune Response
Secretion
Cell Division

PTMs

Phosphorylation
Sumoylation
Deacetylation

Cleavage
Methylation
Acetylation

Ubiquitination

Research Areas

Cancer
Innate Immunity
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZBTB16

References

PMID: 8384553 by Chen Z., et al. Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.

PMID: 10500192 by Zhang T., et al. Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene.

1 Publications of Boster ZBTB16 Antibodies & ELISA Kits

PubMed ID: 32216931, Shi L,Duan Y,Yao X,Song R,Ren Y.Effects of selenium on the proliferation and apo...

*More publications can be found for each product on its corresponding product page