ZAP70 Antibodies

AND ZAP70 ELISA kits, ZAP70 Proteins

Many biological assays use antibodies to detect ZAP70, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZAP70 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZAP70 antibodies...

We validate the specificity of these antibodies to ZAP70 by testing them on tissues known to express ZAP70 positively and negatively. Browse below to find the ZAP70 antibody that suites your experiment. We have 18 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZAP70 Infographic by Boster Bio

All ZAP70 Products

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Product

Figures

Specificity

Applications

Price

Anti-ZAP70 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PB9968
100 μg/vial

Anti-ZAP70 (Chronic Lymphocytic Leukemia Marker) Monoclonal Antibody

7 Q&As

Human

IHC

$486
Cat # M00754-1
100ug/vial

Anti-ZAP70 Monoclonal Antibody

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M00754-3
100 μl

Anti-Zap-70 (Ab-319) Antibody

Human, Mouse, Rat

IHC, WB

$360
Cat # A00754
100 µl

ZAP-70 (Phospho-Tyr292) Colorimetric Cell-Based ELISA Kit

Human, Mouse

ELISA

$540
Cat # EKC2136
1 kit, containing two 96-well plates and all necessary reagents

ZAP-70 (Phospho-Tyr315) Colorimetric Cell-Based ELISA Kit

Human, Mouse

ELISA

$540
Cat # EKC2137
1 kit, containing two 96-well plates and all necessary reagents

ZAP-70 (Phospho-Tyr493) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2540
1 kit, containing two 96-well plates and all necessary reagents

Anti-ZAP70 Antibody Picoband®(monoclonal, 6F12)

Human, Mouse

Flow Cytometry, WB

$370
Cat # M00754-4
100 μg/vial

Anti-ZAP70 Antibody Picoband® (monoclonal, 9D5)

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M00754-5
100 μg/vial

Anti-ZAP70 (Tyr292) Antibody

Human, Mouse

$405
Cat # A00754Y292
100ul

Anti-ZAP70 (T286) Antibody

Human, Rat

IHC, WB

$405
Cat # A00754T286
100ul

Anti-ZAP70 (S313) Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A00754S313
100ul

Anti-ZAP70 (phospho-Y315) Antibody

Human, Mouse, Rat

IHC, WB

$482
Cat # A00754Y315
100ul

Anti-Tyrosine-protein kinase ZAP-70 ZAP70 Antibody

Human

Flow Cytometry, IP, IHC, ICC, WB

$405
Cat # A00754-1
100ul

Anti-Phospho-ZAP-70 (Y319) Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A00754Y319
100ul

Anti-Phospho-ZAP-70 (Y493) Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A00754Y493
100ul

Anti-Zap70 Antibody

Human, Mouse

Flow Cytometry, IF, WB

$299
Cat # M00754-2
80 µl

ZAP70 (NM_001079) Human Over-expression Lysate

Human

$628
Cat # LS007535
100 µg

ZAP70 Overview

Facts about Tyrosine-protein kinase ZAP-70.

ZAP70 3D structure. Source: alphafold

Tyrosine-protein kinase ZAP-70 (ZAP70)

Tyrosine kinase that plays a vital role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, in addition to thymocyte development.

Contributes also into the activation and development of primary B-lymphocytes. When antigen presenting cells (APC) trigger T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 into the doubly phosphorylated TCR component CD247/CD3Z through ITAM motif in the plasma membrane.

Gene Information

Human
Gene Name:	ZAP70
Uniprot:	P43403
Entrez:	7535

Family

Belongs to:

protein kinase superfamily

Alternative Names

70 kDa zeta-associated protein; EC 2.7.10; EC 2.7.10.2; mrtle; mur; SRK; SRKFLJ17679; STD; STDFLJ17670; Syk-related tyrosine kinase; tyrosine-protein kinase ZAP-70; TZK; ZAP70; ZAP-70; zeta-chain (TCR) associated protein kinase (70 kD); zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD

Molecular Weight

Mass (kDA):
69.872 kDA

Genomic Context


Human

Location:	2q11.2
Sequence:	2; NC_000002.12 (97712030..97744327)

Tissue Specificity

Expressed in T- and natural killer cells. Also present in early thymocytes and pro/pre B-cells.

Subcellular Localizations

Cytoplasm. Cell membrane; Peripheral membrane protein. In quiescent T-lymphocytes, it is cytoplasmic. Upon TCR activation, it is recruited at the plasma membrane by interacting with CD247/CD3Z. Colocalizes together with RHOH in the immunological synapse. RHOH is required for its proper localization to the cell membrane and cytoskeleton fractions in the thymocytes (By similarity).