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- Table of Contents
Facts about Synaptobrevin homolog YKT6.
Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.
Human | |
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Gene Name: | YKT6 |
Uniprot: | O15498 |
Entrez: | 10652 |
Belongs to: |
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synaptobrevin family |
EC 2.3.1; EC 2.3.1.-; R-SNARE; S. cerevisiae, homolog of; SNARE protein Ykt6; synaptobrevin homolog YKT6; YKT6 v-SNARE homolog (S. cerevisiae); YKT6 v-SNARE protein
Mass (kDA):
22.418 kDA
Human | |
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Location: | 7p13 |
Sequence: | 7; NC_000007.14 (44200978..44214294) |
Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Probably cycles through vesicles between Golgi and endosomes.
PMID: 9211930 by McNew J.A., et al. Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport.
PMID: 15479160 by Veit M.; The human SNARE protein Ykt6 mediates its own palmitoylation at C- terminal cysteine residues.