DMRT2 Antibodies

AND DMRT2 ELISA kits, DMRT2 Proteins

Many biological assays use antibodies to detect DMRT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DMRT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DMRT2 antibodies...

We validate the specificity of these antibodies to DMRT2 by testing them on tissues known to express DMRT2 positively and negatively. Browse below to find the DMRT2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DMRT2 Infographic by Boster Bio

All DMRT2 Products

Product

Figures

Specificity

Applications

Price

Anti-DMRT2 Antibody (Center)

Human

$298
Cat # M10308
50 µl

DMRT2 (NM_181872) Human Over-expression Lysate

Human

$960
Cat # LS010655
100 µg

DMRT2 Overview

Facts about Doublesex- and mab-3-related transcription factor 2.

DMRT2 3D structure. Source: alphafold

Doublesex- and mab-3-related transcription factor 2 (DMRT2)

Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome.

Required for the initiation and/or maintenance of proper business of the sclerotome, dermomyotome and myotome (By similarity). .

Gene Information

Human
Gene Name:	DMRT2
Uniprot:	Q9Y5R5
Entrez:	10655

Family

Belongs to:

DMRT family

Alternative Names

doublesex and mab-3 related transcription factor 2; doublesex- and mab-3-related transcription factor 2; Doublesex-like 2 protein; DSXL2; DSXL-2; terra-like protein

Molecular Weight

Mass (kDA):
61.814 kDA

Genomic Context


Human

Location:	9p24.3
Sequence:	9; NC_000009.12 (1003237..1057554)

Tissue Specificity

Expressed in testis, kidney and skeletal muscle.

Subcellular Localizations

Nucleus.

Diseases

Disorders Of Sex Development
Congenital Abnormality
Gonadal Dysgenesis
Monosomy
Malignant Neoplasms
Haploinsufficiency
Xy Female
Malnutrition
Neoplasm By Morphology
Spermatogenesis Arrest
Kidney Neoplasm

Chromosome 9p Deletion Syndrome
Infertility
Carcinoma
Congenital Anomaly Of Face
Neoplasms
Renal Cell Carcinoma

Pathways

Sex Determination
Somitogenesis
Localization
Neurogenesis
Sex Differentiation
Transport
Cell Proliferation
Gastrulation
Proteolysis
Larval Development
Regulation Of Gene Expression
Somite Development
Insemination

Spermatogenesis
Regeneration
Cell Death
Hatching
Dedifferentiation
Neural Tube Patterning
Segmentation

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DMRT2

References

PMID: 10332030 by Raymond C.S., et al. A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators.

PMID: 10729224 by Ottolenghi C., et al. The human doublesex-related gene, DMRT2, is homologous to a gene involved in somitogenesis and encodes a potential bicistronic transcript.