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Y-box-binding protein 2 Antibodies
AND YBX2 ELISA kits, Y-box-binding protein 2 Proteins
Many biological assays use antibodies to detect Y-box-binding protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Y-box-binding protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Y-box-binding protein 2 antibodies...
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YBX2 Infographic by Boster Bio
All YBX2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$449
Cat # A08610
0.1 mg
Cat # A08610
0.1 mg
Human, Mouse, Rat
IHC, WB
$523
Cat # M08610-1
100 µl
Cat # M08610-1
100 µl
Human, Mouse, Rat
IHC, WB
$523
Cat # M08610
100 µl
Cat # M08610
100 µl
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A08610-2
100 μg/vial
Cat # A08610-2
100 μg/vial
YBX2 Overview
Facts about Y-box-binding protein 2.
Y-box-binding protein 2 (YBX2)
Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element.
Binds to full-length mRNA with high affinity in a sequence-independent method. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity.
Gene Information
| Human | |
|---|---|
| Gene Name: | YBX2 |
| Uniprot: | Q9Y2T7 |
| Entrez: | 51087 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Contrin; CSDA3MGC45104; DBPC; DNA-binding protein C; Germ cell-specific Y-box-binding protein; MSY2 homolog; MSY2germ cell specific Y-box binding protein; Y box binding protein 2; Y-box-binding protein 2
Molecular Weight
Mass (kDA):
38.518 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.1 |
| Sequence: | 17; NC_000017.11 (7288254..7294639, complement) |
Tissue Specificity
Expressed in oocytes and testicular germ cells in the stage of spermatogonia to spermatocyte. Also observed placental trophoblasts, as well as in vascular smooth muscle cells in the pulmonary artery, myocardium, and skeletal muscle. Undetectable in epithelial cells in respiratory, gastrointestinal, and urogenital tracts. Up-regulated in various carcinomas and germ cell tumors (at protein level).
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Infertility
- Male Infertility
- Azoospermia
- Female Infertility
- Neoplasms
- Oligospermia
- Dysgerminoma
- Testicular Neoplasms
- Anovulation
- Seminoma
- Spermatogenesis Arrest
- Testicular Seminoma
- Spermatogenesis Abnormal
Pathways
- Spermatogenesis
- Translation
- Oocyte Maturation
- Localization
- Meiosis
- Oocyte Growth
- Metaphase
- Transport
- Diplotene
- Fertilization
- Oogenesis
- Intracellular Transport
- Cell Development
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/YBX2
bosterbio.com/bosterbio-gene-info-cards/YBX2
References
PMID: 10100484 by Tekur S., et al. Contrin, the human homologue of a germ-cell Y-box-binding protein: cloning, expression, and chromosomal localization.
PMID: 16479255 by Kohno Y., et al. Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen.