Exportin-7 Antibodies

AND XPO7 ELISA kits, Exportin-7 Proteins

Many biological assays use antibodies to detect Exportin-7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Exportin-7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Exportin-7 antibodies...

We validate the specificity of these antibodies to Exportin-7 by testing them on tissues known to express XPO7 positively and negatively. Browse below to find the XPO7 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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XPO7 Infographic by Boster Bio

All XPO7 Products

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Price

Anti-Exportin-7 XPO7 Antibody

Human, Mouse, Rat

$405
Cat # A09310
100ul

RanBP16 (XPO7) (NM_015024) Human Over-expression Lysate

Human

$628
Cat # LS023039
100 µg

XPO7 Overview

Facts about Exportin-7.

XPO7 3D structure. Source: alphafold

Exportin-7 (XPO7)

Mediates the nuclear export of proteins (cargos) with wide substrate specificity. From the nucleus binds cooperatively to its cargo and into the GTPase Ran in its active GTP-bound form.

Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complicated and hydrolysis of Ran-GTP into Ran-GDP (triggered by RANBP1 and RANGAP1, respectively) trigger release of the cargo in the export receptor.

Gene Information

Human
Gene Name:	XPO7
Uniprot:	Q9UIA9
Entrez:	23039

Family

Belongs to:

exportin family

Alternative Names

EXP7; exportin 7; KIAA0745exportin-7; RAN binding protein 16; Ran-binding protein 16; RANBP16Exp7

Molecular Weight

Mass (kDA):
123.907 kDA

Genomic Context


Human

Location:	8p21.3
Sequence:	8; NC_000008.11 (21919662..22006585)

Tissue Specificity

Strong expression in testis, thyroid and bone marrow, low expression in lung, liver and small intestine, no expression in thymus, and remaining tissues studied have moderate expression. Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology.