5'-3' exoribonuclease 2 Antibodies

AND XRN2 ELISA kits, 5'-3' exoribonuclease 2 Proteins

Many biological assays use antibodies to detect 5'-3' exoribonuclease 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with 5'-3' exoribonuclease 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop 5'-3' exoribonuclease 2 antibodies...

We validate the specificity of these antibodies to 5'-3' exoribonuclease 2 by testing them on tissues known to express XRN2 positively and negatively. Browse below to find the XRN2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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XRN2 Infographic by Boster Bio

All XRN2 Products

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Product

Figures

Specificity

Applications

Price

Anti-5'-3' exoribonuclease 2 XRN2 Antibody

6 Q&As

Human, Monkey, Mouse

$399
Cat # A02797
100μl

Anti-5'-3' exoribonuclease 2 XRN2 Antibody

Human, Mouse, Rat

$405
Cat # A02797-1
100ul

Anti-5'-3' exoribonuclease 2 XRN2 Antibody

Human, Monkey, Mouse

ELISA, IHC, WB

$380
Cat # A02797-2
100ul

Anti-XRN2 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A02797-3
100 μg/vial

Anti-XRN2 Mouse Monoclonal Antibody [Clone ID: OTI5F4]

+15

Human, Mouse, Rat

IHC, WB

$523
Cat # M02797
100 µl

XRN2 (NM_012255) Human Over-expression Lysate

Human

$960
Cat # LS022803
100 µg

XRN2 Overview

Facts about 5'-3' exoribonuclease 2.

XRN2 3D structure. Source: alphafold

5'-3' exoribonuclease 2 (XRN2)

Possesses 5'->3' exoribonuclease activity (By similarity). May promote the conclusion of transcription by RNA polymerase II.

During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment that is then processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment at this protein can promote termination of transcription.

Gene Information

Human
Gene Name:	XRN2
Uniprot:	Q9H0D6
Entrez:	22803

Family

Belongs to:

5'-3' exonuclease family

Alternative Names

5'-3' exoribonuclease 2; Dhm1-like protein (mouse homolog); DHM1-like protein; DHP protein; EC 3.1.13; EC 3.1.13.-

Molecular Weight

Mass (kDA):
108.582 kDA

Genomic Context


Human

Location:	20p11.22
Sequence:	20; NC_000020.11 (21303313..21389825)

Tissue Specificity

Expressed in the spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocytes, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Isoform 2 is expressed predominantly in peripheral blood leukocytes.