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- Table of Contents
Facts about WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2.
Inhibits the biological action of mature myostatin, but not activin (By similarity). .
Human | |
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Gene Name: | WFIKKN2 |
Uniprot: | Q8TEU8 |
Entrez: | 124857 |
Belongs to: |
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WFIKKN family |
GASP1; GASP-1; Growth and differentiation factor-associated serum protein 1; hGASP-1; WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-relatedprotein; WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2; WAP, FS, Ig, two KU and NTR module related protein; WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2; WFIKKN2; WFIKKN-related protein; WFIKKNRP; WFIKKNRPmultivalent protease inhibitor protein
Mass (kDA):
63.941 kDA
Human | |
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Location: | 17q21.33 |
Sequence: | 17; NC_000017.11 (50834584..50842353) |
Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney.
Secreted.
PMID: 11928817 by Trexler M., et al. Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules.
PMID: 12595574 by Hill J.J., et al. Regulation of myostatin in vivo by growth and differentiation factor- associated serum protein-1: a novel protein with protease inhibitor and follistatin domains.