Protein KIBRA Antibodies

AND WWC1 ELISA kits, Protein KIBRA Proteins

Many biological assays use antibodies to detect Protein KIBRA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein KIBRA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein KIBRA antibodies...

We validate the specificity of these antibodies to Protein KIBRA by testing them on tissues known to express WWC1 positively and negatively. Browse below to find the WWC1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WWC1 Infographic by Boster Bio

All WWC1 Products

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Specificity

Applications

Price

Anti-Protein KIBRA WWC1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A02837
0.1 mg

Anti-KIBRA/WWC1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02837-2
100 μg/vial

Human WWC1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ8IX03
Starting from 20ug

Anti-KIBRA (WWC1) Mouse Monoclonal Antibody [Clone ID: OTI1H8]

Human, Mouse, Rat

$523
Cat # M02837
100 µl

WWC1 Overview

Facts about Protein KIBRA.

WWC1 3D structure. Source: alphafold

Protein KIBRA (WWC1)

Probable regulator of this Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway.

Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of this ERK/MAPK cascade.

Gene Information

Human
Gene Name:	WWC1
Uniprot:	Q8IX03
Entrez:	23286

Family

Belongs to:

WWC family

Alternative Names

FLJ10865; FLJ23369; HBeAg-binding protein 3; KIAA0869HBEBP3; KIBRAHBEBP36; Kidney and brain protein; protein KIBRA; protein WWC1; WW and C2 domain containing 1; WW domain-containing protein 1; WW, C2 and coiled-coil domain containing 1

Molecular Weight

Mass (kDA):
125.301 kDA

Genomic Context


Human

Location:	5q34
Sequence:	5; NC_000005.10 (168291645..168472303)

Tissue Specificity

Expressed in mammary epithelial cells and breast cancer cell lines. Found in the luminal epithelium surrounding the ducts in the normal breast. In the brain, expressed in somatodendritic compartment of neurons in the cortex and hippocampus and in the cerebellum it is found in the Purkinje cells and some granule cells (at protein level). Detected in brain, heart, colon and kidney. In the kidney, expressed in glomerular podocytes, in some tubules and in the collecting duct.